0000000000907902
AUTHOR
Egidio Guglielmini
showing 32 related works from this author
Vitamin A, E, D, B Complex and Homocysteine plasma levels in patients with Alzheimer Disease
2006
Molecular analysis of the APP gene overexpression and his relationship with early onset of Alzheimer Dementia in young adults with Down Syndrome
2004
Mutation analysis of the ΔR 608 mutation causing Niemann-Pick disease type B from blood spot cards in sicilian people
2004
Blood lipids, homocysteine, stress factors, and vitamins in clinically stable multiple sclerosis patients
2009
Abstract Multiple Sclerosis (MS) patients present a decrease of antioxidants and neuroprotective and immunoregulatory vitamins and an increase of total homocysteine (tHcy), cholesterol (CHL), HDL-cholesterol, and of cellular stress markers, variably associated with the different phases of the disease. We compared the blood levels of uric acid, folic acid, vitamins B12, A, and E, tHcy, CHL, HDL-cholesterol, and triglycerides in forty MS patients during a phase of clinical inactivity with those of eighty healthy controls, matched for age and sex. We found higher levels of tHcy (p = 0.032) and of HDL-cholesterol (p = 0.001) and lower levels of vitamin E (p = 0.001) and the ratio vitamin E/CHL …
Methionine synthase reductase (MTRR) A66G polymorphism is not related to plasma homocysteine concentration and the risk for vascular disease.
2009
Epidemiological evidence has revealed that hyperhomocysteinemia increases the risk for vascular disease. Methionine Synthase Reductase (MTRR) is one of several key enzymes in the homocysteine metabolic pathway and its mutant forms have been implicated in abnormal homocysteine accumulation. In this study, we determined total plasma homocysteine levels and MTRR A66G polymorphism in 114 patients with vascular disease: 58 patients with deep-vein thrombosis, 56 patients with arterial thrombosis, and 95 healthy subjects from the Sicilian population. Our data confirmed that, as already reported, moderately elevated t-Hcy levels are correlated with an increased risk of vascular disease. In our stud…
Bone metabolism and oxidative stress in post-menopausal women
2006
Biochimica e Fisiopatologia delle Specie Reattive dell’Ossigeno
2005
Metabolic sindrome and increased risk for cardiovascular disease
2005
Assunzione di alcool e markers di abuso
2004
Potential role of Vitamin K2 plasma levels determination in Alzheimer's Disease
2007
Effects of polymorphism of Methionine Synthase Reductase on total plasma homocysteine in Sicilian populations
2007
LINEE GUIDA PER L'ANALISI DELLE SOSTANZE D'ABUSO IN CAMPIONI BIOLOGICI
2004
Serum acid homocysteine, oxidative stress markers and vitamins in multiple sclerosis
2006
Homocysteine and S-adenosylated metabolites in cardiovascular disease
2010
A major unanswered question is whether direct cellular toxicity of homocysteine (Hcy) is causally involved in cardiovascular disease (CVD) in humans or whether homocysteinemia is simply a passive and indirect indicator of a more complex mechanism. Alternatively or additionally, the association between Hcy and CVD may result from its metabolic precursor S-adenosyl-Hcy (SAH), or from the altered ratio of S-adenosylmethionine SAM/SAH. This competition is based on the known effects of these adenosylated metabolites on cellular methylation, disturbances of which may lead to endothelial dysfunction and/ or CVD. Thus, it is of great significance to know how these adenosylated metabolites (SAM, SAH…
GERD patients: a risk group for xerostomia and oral lesions? A case-control syudy
2007
Antioxidant vitamins and homocysteine plasma levels in patients with Alzheimer Disease
2007
Biochimica clinica dello stress ossidativo
2005
Evaluations and new relationships between renal failure and homocysteine plasma levels in patients with chronic renal failure
2004
Vitamin E and vitamin A plasma levels in patients with Mild Cognitive Impairent (MCI)
2007
Plasma homocysteine levels in patients with chronic renal failure.
2004
Vitamin E and endurance exercise.
2007
Plasma homocysteine levels in patients with metabolic syndrome
2005
Valutazione dei livelli ematici di omocisteina, acido folico, vitamine B6 e B12 in soggetti anziani con funzioni cognitive alterate in seguito a stro…
2004
bone metabolism and oxidative stress in post-menopausal women
2007
Evaluation of plasma homocysteine levels and metabolic sindrome in patients with cardiovascular disease
2005
Plasma omocysteine levels in patients with chronic renal failure
2004
SERUM URIC ACID, HOMOCYSTEINE, OXIDATIVE STRESS MARKERS AND VITAMINS IN MULTIPLE SCLEROSIS.
2006
Evaluation of patients with thrombotic stroke by methionine loading oral curve
2004
POSITIVE ASSOCIATION BETWEEN SERUM VITAMIN K LEVEL AND BONE MINERAL DENSITY
2005
Introduction: Vitamin K is well known for its role in the synthesis of many blood coagulation factors. Also, vitamin K-dependent proteins are very important for bone and vascular health. Vitamin K is known to influence bone metabolism by facilitating the synthesis of osteocalcin because is required for the γ-carboxylation of specific glutamic acid residues, wich in turn, allows a firm binding of calcium ions. The bone mineral density decreases drastically after menopause. Recent studies have been shown that vitamin k influences bone mineral density in osteoporotic people and also actually reduce fracture rates. Many factors influence the individual risk of osteoporosis: genetic predispositi…
Curva da carico orale di metionina nella valutazione di pazienti affetti da patologia trombotica
2004
Blood lipid, homocysteine, uric acid and vitamins in clinically stable Multiple Sclerosis patients
2008
A decrease of antioxidants, of neuroprotective and immunoregulatory vitamins and an increase of total-Homocysteine, Cholesterol, HDL-cholesterol, and of cellular stress markers [1] was reported in patients affected by Multiple Sclerosis. Recently, considering their unreliability, mainly due to the variability of the samples investigated, the attention focused on clinical relapse that results associated to a decrease of Uric acid and an increase of Cholesterol and stress markers. Aim. To identify the biochemical status during Multiple Sclerosis (MS) in a phase of clinical stability (PCS), we compared the blood levels of Urico acid (UA), Folic acid (FA), vitamins B12, A, and E, total-Homocyst…