0000000000907985
AUTHOR
Giuseppe Costanza
showing 49 related works from this author
Intermittent intramuscular clodronate therapy: a valuable option for older osteoporotic women
2005
Diuretic Therapy in Old Patients
1984
The administration of diuretics is indicated in several clinical conditions characterized by more or less severe water and salt retention (congestive heart failure, non-compensated liver cirrhosis, renal syndromes etc.), or in cases in which water and sodium depletion is supposed to improve some pathophysiological aspects of clinical symptoms (e. g. as background treatment in arterial hypertension, or as emergency treatment in left ventricular failure.
Age, homocysteine, and oxidative stress: Relation to hypertension and type 2 diabetes mellitus
2010
Abstract OBJECTIVES: Hyperhomocysteinemia and oxidative stress are independent risk factors for cardiovascular events, which occur more frequently in old age. We evaluated these parameters in relation to age and the presence of hypertension and type 2 diabetes mellitus. METHODS: Two hundred eighty-two subjects (female/male: 142/140; 141 were >65 years and 141 were <65 years; mean age 73.9 +/- 6.6 years and 52.5 +/- 8.2 years, respectively) were randomly recruited from those attending our institution. Blood pressure, anthropometric parameters, oxidative stress parameters (reactive oxygen species [ROS] and malondialdehyde [MDA]), and homocysteine levels were evaluated in participants. RESULTS…
AZITHROMYCIN IN AN OLDER WOMAN WITH DIABETIC GASTROPARESIS
2008
Diabetic neuropathy is a common chronic complication of diabetes and cause of significant morbidity and mortality, because it may involve the autonomous and peripheral nervous systems. Autonomic diabetic neuropathy is a challenging chronic complication of long-standing diabetes manifested with hypotension, syncope, gastroparesis, diarrhea, constipation, bladder dysfunction, sexual dysfunction, cardiac arrest, and/or sudden death. We present a case of diabetic gastroparesis in an older woman. The patient was an 83-year-old woman with a 40-year history of type 2 diabetes who was admitted with hypoglycemia, malnutrition, persistent vomiting, and obstinate constipation. After several unsuccessf…
MAGNESIUM METABOLISM IN INSULIN RESISTANCE, METABOLIC SYNDROME, AND TYPE 2 DIABETES MELLITUS
2007
Magnesium plays a key role in regulating insulin action, insulin-mediated glucose uptake, and vascular tone. Intracellular magnesium depletion may result in a defective tyrosine—kinase activity at the insulin receptor level, in a postreceptorial impairment in insulin action, and clinically in a worsening of insulin resistance. Intra- and extracellular alterations of magnesium metabolism have been identified in clinical states characterized by insulin resistance, such as metabolic syndrome, hypertension, altered glucose tolerance, type 2 diabetes, and aging. Several studies, from our and other’s groups, have confi rmed the clinical relevance of alterations of magnesium homeostasis in these c…
Cardiovascular risk factors in centenarians"
2008
Several studies have shown that centenarians have better cardiovascular risk profiles compared to younger old people. Some reports have revealed that cardiovascular diseases (i.e. hypertension, diabetes, angina and/or myocardial infarction) are less common in centenarians respect to 70 and 80 years old persons. In order to explain this evidence, there is a growing number of hypothesis that consider a combination of genetic factors and lifestyle aspects to elucidate the exceptional longevity of centenarians, able to overcome the most frequent mortality cause, which is a cardiovascular event. It has been suggested that a role on this better cardiovascular risk profile may be played by the inc…
Oral Magnesium Supplementation and Endothelial Function in diabetic and Hypertensive Older Patients
2007
DEPRESSION, SELF-RATED HEALTH STATUS AND DISABILITY THE EUROPEAN STUDY ON ADULT WELL-BEING (ESAW)
2009
Ecocolordoppler epiaortico e transcranico nelle diagnosi differenziale delle demenze
2004
Tumore gastrointesinale indifferenziato (GIST)e pregressa Billroth II in un paziente anziano: solo casualità?
2004
222. DEPRESSIONE E M. DI PARKINSON: VALUTAZIONE DEL TONO DELL’UMORE IN 20 PAZIENTI ULTRASETTANTENNI IN TRATTAMENTO CON L-DOPA E/O DOPAMINO-AGONISTI. …
2005
ANEMIA E DECLINO FUNZIONALE NELL’ANZIANO
2004
Violenza contro le persone anziane
2005
Abuse against elderly persons is extremely frequent, although very often is not declared, and entails high human and financial costs. There are on the whole three types of abuse including domestic, institutional, and auto inflicted. It is difficult to get enough information to define the real dimension of the problem, but data from the National Elder Abuse Incidence Study (NEAIS) describe an increasing and expanding phenomenon. The large proportions of this type of violence has lead the World Health Organization to propose strategies primarily focused on three points: Awareness, Education en Defence. An important role in the prevention and diagnosis of elderly abuse is in the hands of the p…