0000000000908401
AUTHOR
Ville Väyrynen
showing 3 related works from this author
Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases : a population-based study
2020
Background This population‐based study aimed to examine the incidence, patterns and results of multimodal management of metastatic colorectal cancer. Methods A retrospective population‐based study was conducted on patients with metastatic colorectal cancer in Central Finland in 2000–2015. Clinical and histopathological data were retrieved and descriptive analysis was conducted to determine the pattern of metastatic disease, defined as synchronous, early metachronous (within 12 months of diagnosis of primary disease) and late metachronous (more than 12 months after diagnosis). Subgroups were compared for resection and overall survival (OS) rates. Results Of 1671 patients, 296 (17·7 per cent)…
Dialogisen tutkivan oppimisen työtavat vastavalmistuneiden luokanopettajien opetuksessa
2016
Ympäristö- ja luonnontiedon luokanopettajankoulutukseen panostamista ja opettajien jatkokouluttamista suositellaan opetushallituksen (2006) tekemässä luonnontieteiden oppimistulosten arviointia koskevassa tutkimuksessa. (ks. Salmio 2006) Dialoginen tutkiva oppiminen on yksi vaihtoehto kehittää luon-nontieteiden opetuksen laatua sekä lisätä oppilaiden mielenkiintoa luonnon-tieteitä kohtaan. Dialoginen tutkiva oppiminen pitää sisällään tutkivan oppi-misen ja dialogisen opettamisen suosituksia. Luonnontieteen tutkijoilla, päät-täjillä ja opetussuunnitelmien tekijöillä on yhtenäinen näkemys siitä, että tut-kivaan oppimisen työtapoja käyttämällä saadaan kehitettyä oppilaiden luon-nontieteellistä…
Impact of Age and Comorbidity on Multimodal Management and Survival from Colorectal Cancer : A Population-Based Study
2021
This retrospective population-based study examined the impact of age and comorbidity burden on multimodal management and survival from colorectal cancer (CRC). From 2000 to 2015, 1479 consecutive patients, who underwent surgical resection for CRC, were reviewed for age-adjusted Charlson comorbidity index (ACCI) including 19 well-defined weighted comorbidities. The impact of ACCI on multimodal management and survival was compared between low (score 0–2), intermediate (score 3) and high ACCI (score ≥ 4) groups. Changes in treatment from 2000 to 2015 were seen next to a major increase of laparoscopic surgery, increased use of adjuvant chemotherapy and an intensified treatment of metastatic dis…