0000000000908430

AUTHOR

Pedone Claudio

showing 4 related works from this author

Difference in Mortality Risk in Elderly People with Bronchial Obstruction Diagnosed Using a Fixed Cutoff or the Lower Limit of Normal of the FEV1/FVC…

2017

Background: Whether a fixed cutoff or the lower limit of normal of the FEV1/FVC ratio should be used to diagnose bronchial obstruction is still a matter of debate. This issue is particularly important for elderly people. Objectives: We used equations applicable up to 90 years of age to evaluate the mortality of elderly people diagnosed with bronchial obstruction using either a fixed cutoff of 0.7 or the lower limit of normal (LLN). Methods: Participants in the SaRA (Salute Respiratoria nell'Anziano, Italian for "Respiratory Health in the Elderly") study were grouped as follows: FEV1/FVC ≥0.7 and ≥ LLN (n = 535: F-/L-), FEV1/FVC <0.7 but ≥ LLN (n = 118: F+/L-), and FEV1/FVC <0.7 and < LLN (n…

Aged 80 and overMalePulmonary and Respiratory MedicineVital CapacityBronchial obstructionSettore MED/10 - Malattie Dell'Apparato RespiratorioRisk AssessmentLower limit of normalAlgorithmFixed cutoffElderlyItalyForced Expiratory VolumeHumansFemaleLung Diseases ObstructiveAlgorithmsAgedHuman
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Comprehensive geriatric assessment in older people: an umbrella review of health outcomes

2022

Abstract Background Comprehensive geriatric assessment (CGA) has been in use for the last three decades. However, some doubts remain regarding its clinical use. Therefore, we aimed to capture the breadth of outcomes reported and assess the strength of evidence of the use of comprehensive geriatric assessment (CGA) for health outcomes in older persons. Methods Umbrella review of systematic reviews of the use of CGA in older adults searching in Pubmed, Embase, Scopus, Cochrane library and CINHAL until 05 November 2021. All possible health outcomes were eligible. Two independent reviewers extracted key data. The grading of evidence was carried out using the GRADE for intervention studies, whil…

Aged 80 and overAgingumbrella reviewFrailtyOutcome Assessmentcomprehensive geriatric assessment; older people; systematic review; umbrella review; Aged; Aged 80 and over; Humans; Independent Living; Outcome Assessment Health Care; Systematic Reviews as Topic; Frailty; Geriatric AssessmentGeneral Medicinecomprehensive geriatric assessmentcomprehensive geriatric assessment older people systematic review umbrella review Aged Aged 80 and over Humans Independent Living Outcome Assessment Health Care Systematic Reviews as Topic Frailty Geriatric Assessmentolder peopleHealth Caresystematic reviewOutcome Assessment Health Care80 and overHumansIndependent LivingGeriatrics and GerontologyGeriatric Assessmentcomprehensive geriatric assessment ; older people ; systematic review ; umbrella review.AgedSystematic Reviews as Topic
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Chronic renal failure: a neglected comorbidity of COPD

2009

BACKGROUND: To the best of our knowledge, the association between COPD and chronic renal failure (CRF) has never been assessed. Lean mass is frequently reduced in COPD, and the glomerular filtration rate (GFR) might be depressed in spite of normal serum creatinine (concealed CRF). We investigated the prevalence and correlates of both concealed and overt CRF in elderly patients with COPD. METHODS: We evaluated 356 consecutive elderly outpatients with COPD enrolled in the Extrapulmonary Consequences of COPD in the Elderly Study and 290 age-matched outpatients free from COPD. The GFR was estimated using the Modification of Diet in Renal Disease Study Group equation. Patients were categorized a…

Aged 80 and overMaleComorbidityMiddle AgedSettore MED/10 - Malattie Dell'Apparato RespiratorioPulmonary Disease Chronic ObstructiveCOPD ElderlyCase-Control StudiesCreatininePrevalenceHumansKidney Failure ChronicRegression AnalysisFemaleAgedGlomerular Filtration Rate
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Prognostic value of FEV1/FEV6 in elderly people

2010

BACKGROUND: The ratio of forced expiratory volume in 1 s and forced expiratory volume in 6 s (FEV1/FEV6) has been proposed as an alternative for FEV1/forced vital capacity (FVC) to diagnose obstructive diseases with less effort during spirometry; however, its prognostic value is unknown. We evaluated whether FEV1/FEV6 is a significant predictor of mortality in elderly subjects and compared its prognostic value with that of FEV1/FVC and FEV1. METHODS: One thousand nine hundred and seventy-one subjects, aged >65 years, participated in the population-based SA.R.A. study. During the baseline exam, a multidimensional assessment included spirometry. Vital status was determined during 6 years of f…

Lung DiseasesMaleTime FactorsVital CapacityKaplan-Meier EstimateSettore MED/10 - Malattie Dell'Apparato RespiratorioRisk AssessmentPredictive Value of TestsRisk FactorsCause of DeathForced Expiratory VolumeHumansGeriatric AssessmentLungAgedProportional Hazards ModelsAged 80 and overChi-Square DistributionAge FactorsPrognosiselderly lung functionSurvival RateItalyCardiovascular DiseasesSpirometryFemale
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