0000000000909729

AUTHOR

Axel Eickhoff

showing 5 related works from this author

Effect of intravenous application of esomeprazole 40???mg versus pantoprazole 40???mg on 24-hour intragastric pH in healthy adults

2007

BACKGROUND: It has been demonstrated that therapy with proton pump inhibitors reduces recurrence of bleeding following initial endoscopic treatment of bleeding peptic ulcers. AIM: This study compared the effects of esomeprazole 40 mg and pantoprazole 40 mg on intragastric acid control. Both substances were administered intravenously as 15-min infusion and as bolus injection. METHODS: Healthy men and women volunteers were enrolled in this single-center, open, randomized, three-way crossover study. After administration of esomeprazole 40 mg and pantoprazole 40 mg intravenously as 15-min infusion, and pantoprazole 40 mg intravenously as bolus injection, continuous 24-h intragastric pH monitori…

AdultMalemedicine.medical_specialtymedicine.drug_classPepticProton-pump inhibitorPharmacologyGastroenterology2-PyridinylmethylsulfinylbenzimidazolesHelicobacter InfectionsEsomeprazoleGastric AcidInternal medicineHumansMedicineEsomeprazole SodiumInfusions IntravenousPantoprazoleMonitoring PhysiologicPantoprazoleCross-Over StudiesHelicobacter pyloriHepatologybusiness.industryStomachGastroenterologyEsomeprazoleGastric Acidity DeterminationHydrogen-Ion ConcentrationMiddle AgedAnti-Ulcer AgentsCrossover studymedicine.anatomical_structureInjections IntravenousBody ConstitutionGastric acidFemalebusinessmedicine.drugEuropean Journal of Gastroenterology & Hepatology
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Colorectal Polyps: Detection with Dark-Lumen MR Colonography versus Conventional Colonoscopy

2005

To prospectively compare dark-lumen magnetic resonance (MR) colonography with conventional colonoscopy in the detection of colorectal polyps.Local ethical committee approval and informed consent were obtained. One hundred consecutive patients (56 men, 44 women; mean age +/- standard deviation, 67.7 years +/- 14.7; range, 25-82 years) who were referred for conventional colonoscopy from January 2003 to January 2004 underwent MR colonography and conventional colonoscopy after standard precolonoscopic bowel cleansing. Colonoscopy was performed immediately after MR colonography. For MR colonography, the colon was filled with approximately 2000 mL of tap water. Imaging was performed with a 1.5-T …

AdultMalemedicine.medical_specialtyColonic PolypsContrast MediaRectumColonoscopySensitivity and SpecificityImaging Three-DimensionalMegluminePredictive Value of TestsImage Processing Computer-AssistedOrganometallic CompoundsmedicineHumansRadiology Nuclear Medicine and imagingProspective StudiesProspective cohort studyAgedAged 80 and overmedicine.diagnostic_testbusiness.industryMr colonographyMagnetic resonance imagingColonoscopyMiddle AgedMagnetic Resonance ImagingEndoscopyProne positionmedicine.anatomical_structurePredictive value of testsFemaleRadiologybusinessRadiology
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Endoscopic laser palliation for rectal cancer-- therapeutic outcome and complications in eighty-three consecutive patients.

2002

OBJECTIVE The treatment of advanced rectal cancer is still a challenge. We analysed the short-term success, treatment-related complications and the long-term outcome after laser palliation for rectal cancer. METHODS Over a ten-years period eighty-three consecutive patients (median age 81 (46-94) yrs; 43 female) were treated mainly for obstructive symptoms or tumour bleeding. Laser palliation was performed using a Neodymium:Yttrium-Aluminium-Garnet (Nd:YAG) laser. RESULTS The immediate overall-success rate was 96.4 % (80 of 83 patients) and only one female received a diverting colostomy because of an inaccessible high-grade rectal stenosis, initially. During follow-up, eight additional patie…

MaleReoperationmedicine.medical_specialtyColorectal cancermedicine.medical_treatmentRectumProctoscopyRecurrenceOcclusionmedicineHumansHospital MortalityAgedAged 80 and overmedicine.diagnostic_testbusiness.industryRectal NeoplasmsPalliative CareGastroenterologyMiddle Agedmedicine.diseaseAblationEndoscopyDiverting colostomySurgerySurvival Ratemedicine.anatomical_structureRectal DiseasesRectal PerforationFemaleLaser TherapybusinessComplicationGastrointestinal HemorrhageIntestinal ObstructionFollow-Up StudiesZeitschrift fur Gastroenterologie
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Diagnosis of Liver Cirrhosis

2005

Background/goals Liver cirrhosis, the final stage of chronic liver disease, is characterized by an unfavorable prognosis and an increased risk of hepatocellular carcinoma and also requires an appropriate management. Laparoscopy, the gold standard in the diagnosis of cirrhosis, is hampered by its invasiveness. Therefore, a noninvasive method for diagnosing liver cirrhosis would be of great benefit. Study A consecutive series of 100 patients, sent to our gastroenterological unit for diagnostic laparoscopy, underwent a standardized ultrasonographic examination prior to laparoscopy. Results Conventional ultrasonographic examination revealed a sensitivity of 55% and a specificity of 86% in the d…

AdultLiver CirrhosisMalemedicine.medical_specialtyCirrhosisChronic liver diseaseSensitivity and SpecificityGastroenterologyInternal medicineHumansMedicineStage (cooking)LaparoscopyAgedUltrasonographyAged 80 and overChi-Square Distributionmedicine.diagnostic_testbusiness.industryUltrasoundGastroenterologyGold standard (test)Middle Agedmedicine.diseaseEndoscopyHepatocellular carcinomaFemaleLaparoscopyRadiologybusinessJournal of Clinical Gastroenterology
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Bacteremia after diagnostic conventional laparoscopy and minilaparoscopy: a prospective study in 100 patients.

2006

Background/Goals: Diagnostic laparoscopy under sedoanalgesia is a valuable tool in the work-up of liver diseases and is helpful as a staging procedure. The rate of bacteremia caused by this procedure is unknown, in particular when performed as minilaparoscopy. Study: A 100 consecutive patients having undergone diagnostic laparoscopy carried out either conventionally (group I, n = 50) or as minilaparoscopy (group II, n - 50) were prospectively enrolled in this study. Blood cultures were drawn before and within 5 minutes after the procedure. Risk factors for bacteremia were evaluated. Results: Bacterial growth occurred in 4 blood cultures drawn immediately after laparoscopy. No patient develo…

AdultMalemedicine.medical_specialtyGroup iiConventional laparoscopyDiagnostic laparoscopyBacteremiaSedoanalgesiamedicineHumansProspective StudiesLaparoscopyProspective cohort studyGram-Positive Bacterial InfectionsAgedAged 80 and overmedicine.diagnostic_testbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseLaparoscopesEndoscopySurgeryCulture MediaGram-Positive CocciBloodBacteremiaFemaleLaparoscopybusinessJournal of clinical gastroenterology
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