0000000000916423
AUTHOR
Antonella Leone
showing 4 related works from this author
Identification of the plant compound geraniin as a novel Hsp90 inhibitor
2013
Besides its function in normal cellular growth, the molecular chaperone heat shock protein 90 (Hsp90) binds to a large number of client proteins required for promoting cancer cell growth and/or survival. In an effort to discover new small molecules able to inhibit the Hsp90 ATPase and chaperoning activities, we screened, by a surface plasmon resonance assay, a small library including different plant polyphenols. The ellagitannin geraniin, was identified as the most promising molecule, showing a binding affinity to Hsp90α similar to that of 17-(allylamino)-17-demethoxygeldanamycin (17AGG). Geraniin was able to inhibit in vitro the Hsp90α ATPase activity in a dose−dependent manner, with an in…
Jellyfish Impacts on Marine Aquaculture and Fisheries
2020
Over the last 50 years, there has been an increased frequency and severity of negative impacts affecting marine fishery and aquaculture sectors, which claimed significant economic losses due to the interference of stinging gelatinous organisms with daily operational activities. Nevertheless, original scientific information on jellyfish-related incidents, their consequences, and potential preventative and mitigation countermeasures is limited and scattered across gray literature, governmental technical reports, and communication media. A literature scan searching for records of any interactions between jellyfish and the marine fishery/aquaculture sectors were carried out. Out of 553 papers, …
Biochemical characterization of cassiopea andromeda (Forsskål, 1775), another red sea jellyfish in the western mediterranean sea
2021
Increasing frequency of native jellyfish proliferations and massive appearance of non-indigenous jellyfish species recently concur to impact Mediterranean coastal ecosystems and human activities at sea. Nonetheless, jellyfish biomass may represent an exploitable novel resource to coastal communities, with reference to its potential use in the pharmaceutical, nutritional, and nutraceutical Blue Growth sectors. The zooxanthellate jellyfish Cassiopea andromeda, Forsskål, 1775 (Cnidaria, Rhizostomeae) entered the Levant Sea through the Suez Canal and spread towards the Western Mediterranean to reach Malta, Tunisia, and recently also the Italian coasts. Here we report on the biochemical characte…
The use of TikTok in Initial Teacher Training
2023
The continuous evolution of technology and the increasingly massive use of visual content have given way to an era characterized by the use of short videos mainly through social media. Among these applications, TikTok has been chosen primarily by young people thanks to the unique communication strategies it offers. This paper presents the activities that have involved and will involve first-year students enrolled in the single-cycle master’s degree course in Primary Education Sciences of the University of Palermo in the a.y. 2022/2023. This study aims primarily at investigating the perceptions that university students have regarding the use of TikTok to implement learning and to highlight t…