0000000000917361
AUTHOR
F Macaluso
Cardiac progenitor cells and the development of the human heart
Hsp60 levels in the skeletal muscle are fibre-type specific and increase after endurance training
Role of different endurance training programs on cancer cachexia:pointing particular attention to the gender and age differences Macaluso
Evidence from recent publications indicates that repeated exercise may enhance the quality of life of cancer patients (Maddocks et al., 2012). Regular physical activity may attenuate the adverse effects of cancer therapy, prevent or reverse cachexia and improve survival, although not all the patients are able or willing to undertake programs currently being offered. The aims of this study were to analyze: i) the effects of a progressive endurance exercise (progressive Training, pTR) on survival and cachexia in sedentary (SED) mice inoculated (I) with a fresh fragment of solid C26 tumor [SED-I-pTR; SED-I-SED]; ii) the effect of different protocols of endurance exercise (Trained for 30 min, T…
Recovery of damaged skeletal muscle in mdx mice by low-intensity endurance exercise
Biological and metodological bases of muscular stretching
MUSCLE WASTING AND CARDIAC MUSCLE DAMAGE IN CACHECTIC PATIENTS
Muscle wasting is a degeneration of the muscle tissue that can derive from several patho-logical situations, but most of the times is caused by a condition of cachexia in patients with cancer or other diseases. This degeneration results from a decrease in protein syn-thesis and an increase in protein degradation. This is caused mainly by the overexpres-sion of ubiquitin-proteosome-system (UPS) elements, under the control of factors re-leased in cachexia that lead cells toward a catabolic rather than an anabolic pathway. Both skeletal and cardiac muscles can be affected by muscle wasting and until now an effective treatment is unknown. Only experimental trials of exercise training bring to a…
ANALYSIS OF INDUCIBLE NITRIC OXIDE SYNTHASE AND HYPOXIA-INDUCIBLE FACTOR-1ALPHA IN THE VASCULAR REMODELLING OF EXERCISED MOUSE HEARTS
Bronchial epithelial thickness is increased in small airways of MDX mise at rest and after training
Increased bronchial epithelial thickness in small airways of mdx mice at rest and after exercise training
Hsp60 expression in skeletal muscle increase after endurance training
Effects of water temperature on swimmers
alphaB-crystallin modulation after acute exercise in skeletal muscle: the role of oxidative stress and fiber composition
INSULIN RESISTANCE, STEATOSIS AND PROGRESSION OF FIBROSIS IN PATIENTS WITH GENOTYPE 1 CHRONIC HEPATITIS C
Background and aim: Insulin resistance (IR) and steatosis have been associated with fibrosis severity in chronic hepatitis C (CHC), but only few studies investigate their role as predictors of disease evolution. We aimed to assess in patients with CHC if IR and steatosis are linked to progression of fibrosis over time. Material and methods: 86 consecutive G1 HCV infected patients with two paired liver biopsies over a period 67±30 months (range, 13-135), were evaluated at baseline by anthropometric and metabolic measurements, including IR (IR= HOMA-IR >2.7). All biopsies were scored by one pathologist for staging and grading (Scheuer). Steatosis was considered significant if =10. Results: At…
EFFECTS OF CONJUGATED LINOLEIC ACID AND RESISTANCE TRAINING IN RECREATIONAL ATHLETES
Conjugated linoleic acid (CLA) is a mixture of positional and geometrical isomers of linoleic acid, that are known to posses several physiological effects such as enhancing immune response, reducing arteriosclerosis risk, and inhibiting carcinogenesis. Over the last decade, the use of CLA supplement has become widespread among elite and recreational athletes because it should increase training effects, improve fat oxidation, increase energy delivery, reduce body weight, improve lipid profile, and so on. The purpose of this project is to investigate whether CLA supplementation after a resistance training session affects general markers of muscle damage, total testosterone, cortisol and sex h…
Anti-cancer effects of Pleurotus eryngii var. eryngii: an in vitro and in vivo models focusing on Heat Shock Proteins
Heat shock proteins (Hsps) are highly expressed in a variety of cancer cells and are essential to their survival contributing to tumor cell propagation, metastasis, and protection against apoptosis]. Cancer is a leading cause of death worldwide. The current anti-cancer drugs available in market are not target specific and pose several side-effects and complications in clinical management of various forms of cancer, which highlights the urgent need for novel effective and less-toxic therapeutic approaches. Medicinal mushrooms have emerged as wonderful source of nutraceuticals, anti-oxidants, anticancer, prebiotic, anti-inflammatory, cardiovascular, anti-microbial, and anti-diabetic. The ongo…
Increased expression of titin in mouse gastrocnemius muscle after an endurance-training program
Titin, a sarcomeric giant protein, plays crucial roles in muscle assembly, elasticity and stability. Little is known about titin adaptation to endurance exercise. We studied the effects of endurance training on titin expression in mouse gastrocnemius muscles (MGM). Sixty-three ten-week-old male Swiss mice were divided into seven groups. Four groups were composed of untrained control animals (C0, C15, C30, C45) instead the other three included mice trained for 15 (T15), 30 (T30) and 45 (T45) days by treadmill. The training protocol was mainly aerobic, characterized by moderate-intensity, rhythmic and continuous exercises. Titin expression was determined by immunohistochemistry on MGM section…
Analisi della frequenza cardiaca e della concentrazione di lattato ematico in soggetti sovrappeso allenati con uno specifico protocollo di spinning.
Silibin hepatoprotection occur via NFKB signaling inhibition in murine nonalcholic fatty liver disease
Heat shock protein 70 and exercise: morphofunctional relationships
Effects of low intensity endurance training on small airways of MDX mice
Silybin enhances mitochondrial function and inhibits NFkB activation in murine nonalcoholic fatty liver disease
Italian Journal of Anatomy and Embryology, Vol 115, No 1/2 (Supplement) 2010