SUBOXONE EFFICACY IN TREATING DRUG ADDICTION: COMPARISON WITH METHADONE AND MONITORING OF PATIENTS IN THERAPY AT SERT OF MARSALA

Drug dependence and abuse is a public health problem as revealed by reports of state police that account overdoserelated deaths for 305 during 2015. Most of the dead were caused by heroin. Despite evidence that methadone maintenance treatment is effective, it remains a controversial therapy because of its indefinite provision of a dependence-producing medication. The aim of this work is to evaluate clinically the effectiveness of Suboxone in maintaining abstinence and preventing relapse. Suboxone consists of buprenorphine and naloxone in the 4:1 ratio. The former is a partial agonist on the receptor and its absorption is rapid, while Naloxone is an antagonist on the receptor k and it is abs…

DISCHARGE HYDROGRAPH ASSESSMENT THROUGH REVERSE ROUTING MODEL IN RIVERS WITH SIGNIFICANT LATERAL INFLOW