0000000000921501
AUTHOR
Laura Iacorossi
The International Guideline Evaluation Screening Tool (IGEST): development and validation.
Abstract Background Guideline adaptation provides an important alternative to de novo guideline development by making the process more efficient and reducing unnecessary duplication. The quality evaluation of international guidelines is an essential part of the adaptation process. The study aims at describing the development and validation of a new tool to screen trustworthy Clinical Practice Guidelines (CPGs) for their adoption/adaption: the International Guideline Evaluation Screening Tool (IGEST). Methods The process of developing the IGEST involved two main phases: 1) tool development and 2) content validation. The tool development phase comprised three stages, where the scope of the IG…
Chronic non-cancer pain in primary care: an Italian cross-sectional study
Chronic non-cancer pain is a complex health condition that affects more than a quarter of the Italian population who mainly refers to general practitioners and primary care for their treatment. There are little information on the epidemiological and clinical characteristics and types of treatments for these patients who suffer from chronic pain. The aim of the study was to provide epidemiological and clinical information about patients with chronic non-cancer pain who refers to GPs for their treatment. An observational, multicentre, cross-sectional study was carried out using retrospectively reviewed clinical records from 29 GPs. Some pharmacoeconomic aspects were also investigated. A total…
Accuracy of risk tools to predict critical bleeding in major trauma: A systematic review with meta-analysis.
BACKGROUND Early detection of critical bleeding by accurate tools can help ensure rapid delivery of blood products to improve outcomes in major trauma patients. We conducted a systematic review to evaluate the accuracy of risk tools to predict critical bleeding in patients with major trauma. METHODS PubMed, Embase, and CENTRAL were searched up to February 2021 for studies investigating risk tools to predict critical bleeding for major trauma people in prehospital and emergency department. We followed the Preferred Reporting Items for Systematic Review and Meta-Analysis of Diagnostic Test Accuracy study guidelines. Two independent authors included studies, extracted data, appraised the quali…
Effectiveness of Pre-Hospital Tourniquet in Emergency Patients with Major Trauma and Uncontrolled Haemorrhage: A Systematic Review and Meta-Analysis
Trauma is one of the leading causes of uncontrolled haemorrhage, death, and disability. Use of a tourniquet can be considered an optimal anti-haemorrhagic resource, in pre-hospital and emergency settings, and its lifesaving effect is clinically contradictory. This review aims to assess the clinical efficacy of the tourniquet in the emergency pre-hospital care setting for the management of haemorrhage. We conducted the systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, the PRISMA statement. We searched the following electronic databases: EMBASE, MEDLINE, and Cochrane-CENTRAL. All studies included were appraised for risk of bias. Prevalent prim…
Additional file 4 of The International Guideline Evaluation Screening Tool (IGEST): development and validation
Additional file 4.
Additional file 4 of The International Guideline Evaluation Screening Tool (IGEST): development and validation
Additional file 4.
Additional file 3 of The International Guideline Evaluation Screening Tool (IGEST): development and validation
Additional file 3.
Additional file 2 of The International Guideline Evaluation Screening Tool (IGEST): development and validation
Additional file 2.
Chronic Non-cancer Pain Management in a Tertiary Pain Clinic Network: a Retrospective Study
Introduction: Chronic pain is a distressing condition that should be treated in specialized pain clinics. Pain clinics offer a holistic, evidence-based approach, including pharmacological, complementary, and invasive treatments. This study aimed to provide preliminary information regarding chronic pain treatments and identify reasons for accessing an important hub-spoke pain clinic network. Methods: A retrospective multicenter cross-sectional study was carried out. A total of 1606 patients’ records were included. Patients were selected from the 26 pain clinics of a single region in Italy. Univariate and multivariate logistic regression models were used. Results: Multivariate models showed t…
Additional file 1 of Resuscitative endovascular balloon occlusion of the aorta (REBOA) in patients with major trauma and uncontrolled haemorrhagic shock: a systematic review with meta-analysis
Additional file 1.
The efficacy of balneotherapy, mud therapy and spa therapy in patients with osteoarthritis: an overview of reviews.
Osteoarthritis is a degenerative disease considered a leading cause of functional disability. Its treatment is based on a combination of pharmacological and non-pharmacological interventions, but the role of these latter is still debated. This overview of systematic reviews aimed at evaluating the short-term efficacy of different thermal modalities in patients with osteoarthritis. We searched PubMed, Scopus, CINHAL, Web of Science, ProQuest and the Cochrane Database of Systematic Reviews from inception until October 2020, with no language restrictions. We selected the following outcomes a priori: pain, stiffness and quality of life. Seventeen systematic reviews containing 27 unique relevant…
Strategies to exiting the COVID-19 lockdown for workplace and school: A scoping review
Highlights • Epidemiological conditions should be monitored and enforced. • COVID-19 must be under control below thresholds of safeguards. • Testing, contact tracing, and isolation strategies are essential components to ease the lockdown. • The maintenance of social distancing measures is an overarching mitigation strategy. • The benefit gained from the implementation of social distancing was evident.
Additional file 1 of The International Guideline Evaluation Screening Tool (IGEST): development and validation
Additional file 1.
Towards a New System for the Assessment of the Quality in Care Pathways: An Overview of Systematic Reviews.
Clinical or care pathways are developed by a multidisciplinary team of healthcare practitioners, based on clinical evidence, and standardized processes. The evaluation of their framework/content quality is unclear. The aim of this study was to describe which tools and domains are able to critically evaluate the quality of clinical/care pathways. An overview of systematic reviews was conducted, according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses, using Medline, Embase, Science Citation Index, PsychInfo, CINAHL, and Cochrane Library, from 2015 to 2020, and with snowballing methods. The quality of the reviews was assessed with Assessment the Methodology of Systemati…
Face mask use in the Community for Reducing the Spread of COVID-19: a systematic review
ABSTRACTBackgroundEvidence is needed on the effectiveness of wearing face masks in the community to prevent SARS-CoV-2 transmission.MethodsSystematic review and meta-analysis to investigate the efficacy and effectiveness of face mask use in a community setting and to predict the effectiveness of wearing a mask. We searched MEDLINE, EMBASE, SCISEARCH, The Cochrane Library and pre-prints from inception to 22 April 2020 without restriction by language. We rated the certainty of evidence according to Cochrane and GRADE approach.FindingsOur search identified 35 studies, including 3 randomised controlled trials (RCTs) (4017 patients), 10 comparative studies (18984 patients), 13 predictive models,…
Additional file 1 of Accuracy of pre-hospital triage tools for major trauma: a systematic review with meta-analysis and net clinical benefit
Additional file 1: Supplement A. Search strategies. Supplement B. Characteristics of included studies. Supplement C. Accuracy data of pre-hospital tools. Supplement D. Net clinical benefit curves. Supplement E. Quality assessment QUADAS 2. Supplement F. Summary of findings tables.