Author: Marinella Alessi

0000000000925501

AUTHOR

Marinella Alessi

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Increased leptin/leptin receptor pathway affects systemic and airway inflammation in COPD former smokers

2011

Andreina Bruno1, Marinella Alessi2, Simona Soresi2, Anna Bonanno1, Loredana Riccobono1, Angela Marina Montalbano1, Giusy Daniela Albano1, Mark Gjomarkaj1, Mirella Profita11Institute of Biomedicine and Molecular Immunology, Italian National Research Council, Palermo, Italy; 2Dipartimento Biomedico di Biomedicina Interna e Specialistica, University Palermo, ItalyBackground: Leptin, a hormone produced mainly by adipose tissue, regulates food intake and energy expenditure. It is involved in inflammatory diseases such as chronic obstructive pulmonary disease (COPD) and its deficiency is associated with increased susceptibility to the infection. The leptin receptor is expressed in the lung and in…

medicine.medical_specialtyReceptor expressionImmunologyAdipose tissueInflammationsmokersRM1-950Systemic inflammationleptinneutrophilsInternal medicinePathologymedicineCOPDRB1-214Immunology and AllergyOriginal ResearchCOPD smokers inflammation leptin neutrophilsCOPDLeptin receptorbusiness.industryLeptindigestive oral and skin physiologymedicine.diseaseRetractionrespiratory tract diseasesEndocrinologyinflammationImmunologySputumTherapeutics. Pharmacologymedicine.symptomJournal of Inflammation Researchbusinesshormones hormone substitutes and hormone antagonistsJournal of Inflammation Research

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