0000000000946232

AUTHOR

Rafael Botella Estrada

showing 3 related works from this author

Lack of TERT promoter mutations in melanomas with extensive regression

2015

AdultMale0301 basic medicineTelomeraseSkin NeoplasmsDermatologyTert promoter030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicinemedicineHumansPromoter Regions GeneticMelanomaTelomeraseAgedbusiness.industryMelanomaCase-control studyMiddle Agedmedicine.diseaseRegressionNeoplasm regression030104 developmental biologyNeoplasm Regression SpontaneousCase-Control StudiesMutationMutation (genetic algorithm)Cancer researchFemalebusinessJournal of the American Academy of Dermatology
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MicroRNAs expression associated with aggressive clinicopathological features and poor prognosis in primary cutaneous melanomas

2020

Several studies have focused on identifying microRNAs involved in the pathogenesis of melanoma. However, its association with clinicopathological features has been scarcely addressed. The aim of this study is to identify microRNAs expression profiles related to aggressive clinicopathological and molecular features, and to analyze the association with melanoma survival. A retrospective and observational study was performed in a series of 179 formalin-fixed paraffin embedded primary cutaneous melanomas. First, a screening analysis on a discovery set (n = 22) using miRNA gene chip array (Affymetrix, Santa Clara, California, USA) was performed. Differentially expressed microRNAs were detected e…

AdultMale0301 basic medicineCancer ResearchPoor prognosisSkin NeoplasmsTERT mutationsDermatologyBiologyPathogenesisBreslow Thickness03 medical and health sciences0302 clinical medicinemicroRNAmelanomamedicineHumansMelanomaMitosisSurvival analysisAgedMelanomaMicroRNA Expression ProfileMiddle AgedPrognosismedicine.diseasemicroRNAsMicroRNAs030104 developmental biologyOncology030220 oncology & carcinogenesisCancer researchFemaleprognosisclinicopathological featuresMelanoma Research
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Tiña inflamatoria de la mano: la importancia de las pústulas

2017

Tinea manuummedicine.medical_specialtybusiness.industryMEDLINEMedicineGeneral Medicinebusinessmedicine.diseaseDermatologyMedicina Clínica
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