0000000000948527

AUTHOR

R. Barone

showing 14 related works from this author

A brain inspired architecture for an outdoor robot guide

2008

Robotics
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HSP60 is muscle fiber-type specific and increases after endurance training: Mice model

2014

Heat shock protein (Hsp) 60 plays a key role in the translocation of proteins and cytoprotection, is primarily localized inside mitochondrial, and its levels increase in skeletal muscle upon exercise (Folkesson et al., 2013). The aim of this study was to examine muscle fiber specificity of HSP60 at rest and after an endurance training program of 45 days. Forth-eight male young (7-weeks old) healthy mice (BALB/c) were subdivided into six groups (8 mice per group). Three groups were trained on a rota-rod, at a gradually increasing duration and speed; while the other three groups did not perform any type of regular physical activity. One group of each condition was sacrificed after 15, 30 and …

hSP60 endurance trainin
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Comparative analysis of the structure of temporomandibular joint in human and rabbit.

2016

In order to increase knowledge on the morphology and structure of the articular disc of the temporomandibular joint (TMJ) for a better understanding of the functional role of the same, it proceeded with an investigation on histological samples in the block of TMJ and periarticular tissues of adult rabits and human fatustes at different stage of development. (www.actabiomedica.it)

Settore BIO/16 - Anatomia UmanaTemporomandibolar junction anatomy and functional aspects
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Hsp60 expression in skeletal muscle increase after endurance training

2013

hsp60 endurance training fibre type specific
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" Effectiveness of G-CSF+ plerixafor mobilization in B-talassemia patients and whole gene expression analysis of the harvested CD34+ cell"

2014

G-CSF plerixafor CD34+ cell microarray
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Rituximab for managing relapsing or refractory patients with idiopathic thrombotic thrombocytopenic purpura – haemolytic uraemic syndrome

2010

AdultMaleSalvage TherapyAdolescentPurpura Thrombotic ThrombocytopenicADAMTS13 ProteinCase ReportMiddle AgedADAM ProteinsAntibodies Monoclonal Murine-DerivedTreatment OutcomeHumansImmunologic FactorsFemaleRituximabrefractory thrombotic thrombocytopenic purpura
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Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery.

2015

BACKGROUND: Heat shock protein 60 (Hsp60) is a chaperonin involved in tumorigenesis, but its participation in tumor development and progression is not well understood and its value as a tumor biomarker has not been fully elucidated. In the current study, the authors presented evidence supporting the theory that Hsp60 has potential as a biomarker as well as a therapeutic target in patients with large bowel cancer. METHODS: The authors studied a population of 97 subjects, including patients and controls. Immunomorphology, Western blot analysis, and quantitative real-time polymerase chain reaction were performed on tissue specimens. Exosomes were isolated from blood and characterized by electr…

MaleCancer ResearchMacrophageBlotting WesternNatural killer cellEnzyme-Linked Immunosorbent AssayAdenocarcinomaExosomesReal-Time Polymerase Chain ReactionMitochondrial ProteinsHeat shock protein 60 (Hsp60)Biomarkers TumorHumansColon adenocarcinomaAgedColon adenocarcinoma; Exosomes; Heat shock protein 60 (Hsp60); Macrophages; Natural killer cells; Plasma cell membrane; Theranostics; Cancer Research; OncologyAged 80 and overPlasma cell membraneChaperonin 60Middle AgedImmunohistochemistryExosomeTheranosticOncologyColonic NeoplasmsFemaleCancer
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Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study

2021

The outbreak of severe acute respiratory syndromecoronavirus-2, the cause of coronavirus disease 2019 (COVID-19) in December 2019 represented a global emergency accounting for more than 2.5 million deaths worldwide.1 It has had an unprecedented influence on cardiac surgery internationally, resulting in cautious delivery of surgery and restructuring of services.2 Understanding the influence of COVID-19 on patients after cardiac surgery is based on assumptions from other surgical specialties and single-center studies. The COVIDSurg Collaborative conducted a multicenter cohort study, including 1128 patients, across 235 hospitals, from 24 countries demonstrating perioperative COVID-19 infection…

Pulmonary and Respiratory MedicineMale2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)complication.ArticleNOCohort Studiesoutcomes; complications; following cardiac surgery; coronavirus disease 2019Postoperative ComplicationsCardiovascular Diseases; Cohort Studies; Female; Humans; Male; Middle Aged; SARS-CoV-2; COVID-19; Cardiac Surgical Procedures; Postoperative ComplicationsInternal medicineCardiovascular DiseasemedicineCardiac Surgical ProcedureHumansIn patientCardiac Surgical ProceduresLS7_4business.industrySARS-CoV-2COVID-19Middle AgedCardiac surgeryCardiovascular DiseasesoutcomeSurgeryFemaleCohort StudieCardiology and Cardiovascular Medicinebusinesscardiac surgery[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyCohort studyHuman
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Standard di servizio per le comunità terapeutiche per l'infanzia e l'adolescenza. Adattamento alla cultura italiana.

2012

Settore M-PSI/08 - Psicologia ClinicaSettore M-PSI/07 - Psicologia DinamicaComunità terapeutiche per l'infanzia e l'adolescenzaStandard di servizio Infanzia e adolescenza.
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Alcohol, Cannabinoids and Nicotine in liver pathophysiology

2017

The liver can be affected by a wide range of therapeutic and environmental chemicals and here we want to provide a summary of the complex effects of alcohol, cannabinoids and nicotine on liver function. Alcohol is the most important agent that produces liver injury, manifesting as alcoholic fatty liver disease. In addition, it is one of the main etiologic agents for hepatocellular carcinoma development. Studies reviewed in this article regarding cannabinoids, show that Δ9-THC does not produce any harmful effects on the liver, while cannabidiol has hepatoprotective effects in ischemia/reperfusion and alcohol-induced liver injuries. The liver is negatively affected by nicotine exposure, but s…

liver alcohol cannabinoids nicotineLiver -- DiseasesSettore BIO/16 - Anatomia UmanaNicotine -- MetabolismLiver -- PathophysiologyCannabinoids -- Physiological effectAlcohol -- Physiological effectSettore BIO/09 - Fisiologia
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Relapsing or refractory idiopathic thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: the role of rituximab.

2010

thrombotic thrombocytopenic purpura rituximab
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Prevalence and correlates of QTc prolongation in Italian psychiatric care: cross-sectional multicentre study.

2016

Aims.In recent years several warnings have been issued by regulatory authorities on the risk of electrocardiogram abnormalities in individuals exposed to psychotropic drugs. As a consequence of these warnings, monitoring of the QT interval corrected for heart rate (QTc) has become increasingly common. This study was conducted to measure the frequency of QTc prolongation in unselected psychiatric patients, and to document the associated factors using a cross-sectional approach.Method.The study was carried out in 35 Italian psychiatric services that are part of the STAR (Servizi Territoriali Associati per la Ricerca) Network, a research group established to produce scientific knowledge by col…

AdultMalemedicine.medical_specialtyPsychotropic drugsEpidemiologymedicine.medical_treatmentLong QT syndromeAntidepressantDrug overdoseAdverse effectQT intervalAntipsychotic03 medical and health sciencesElectrocardiography0302 clinical medicineRisk FactorsPsychotropic drugmedicinePrevalenceHumanscardiovascular diseasesAntipsychoticAdverse effectPsychiatrySettore MED/25 - PsichiatriaPolypharmacybusiness.industryEnvironmental and Occupational HealthPublic Health Environmental and Occupational HealthAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Epidemiology; Public Health; Environmental and Occupational Health; Psychiatry and Mental HealthOriginal Articlesmedicine.diseaseAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Epidemiology; Public Health Environmental and Occupational Health; Psychiatry and Mental Health030227 psychiatrySubstance abuseLong QT SyndromeCross-Sectional StudiesItalyPsychiatry and Mental HealthPolypharmacyAripiprazoleFemalePublic HealthbusinessAntidepressant; adverse effect; antipsychotic; psychotropic drugsAdverse effect; Antidepressant; Antipsychotic; Psychotropic drugs; Adult; Antipsychotic Agents; Cross-Sectional Studies; Electrocardiography; Female; Humans; Italy; Long QT Syndrome; Male; Prevalence; Risk Factors; Polypharmacy; Epidemiology; Public Health Environmental and Occupational Health; Psychiatry and Mental Health030217 neurology & neurosurgerymedicine.drugAntipsychotic AgentsEpidemiology and psychiatric sciences
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Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score

2021

The British journal of surgery 108(11), 1274-1292 (2021). doi:10.1093/bjs/znab183

Cuidado perioperatorioAcademicSubjects/MED00910Settore MED/18 - CHIRURGIA GENERALEMedizinpulmonary complicationspreoperative screeningDatasets as TopicSurgical Procedures Operative/mortality030230 surgeryperioperative care ; surgical procedures ; operative mortality ; machine learning ; sars-cov-2Medical and Health SciencesProcediments quirúrgicsCohort StudiesMachine LearningTumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14]0302 clinical medicineModelsProcedimientos quirúrgicosMedicine and Health SciencesCOVIDSurg Collaborative Co-authorsMedicine030212 general & internal medicineskin and connective tissue diseasesRapid Research Communication11 Medical and Health SciencesOperative/mortalitySARS-CoV-19COVID-19/mortalityStatisticalCOVID-19/mortality; Cohort Studies; Datasets as Topic; Humans; Machine Learning; Models Statistical; Risk Assessment; SARS-CoV-2; Surgical Procedures Operative/mortalityCOVID-19; Cohort Studies; Datasets as Topic; Humans; Machine Learning; SARS-CoV-2; Surgical Procedures Operative; Models Statistical; Risk AssessmentAprendizaje automáticoOperativeSurgical Procedures OperativeoutcomeOperativo[SDV.IB]Life Sciences [q-bio]/BioengineeringPatient SafetyAcademicSubjects/MED000106.4 SurgeryLife Sciences & BiomedicineHuman61medicine.medical_specialty616.9Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-.Risk AssessmentNOCOVIDSurg CollaborativeVaccine Related03 medical and health sciencesClinical ResearchBiodefenseCures perioperatòriesAprenentatge automàticMortalitatHumansOperatiusLS7_4Surgical ProceduresScience & TechnologyModels Statisticalbusiness.industrySARS-CoV-2SARS-CoV-2 infectionKirurgiPreventionnot indicatedcovid 19fungiEvaluation of treatments and therapeutic interventionsCOVID-19Perioperativecovid 19; pulmonary complications; postoperative mortality risk; SARS-CoV-2 infection; preoperative screening; vaccinationvaccinationmortalityGood Health and Well BeingMortalidadEmergency medicineSurgeryHuman medicineCohort Studiebusinesspostoperative mortality riskPerioperative care
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Autophagic flux restoration by exercise or pharmacological treatment counteracts cancer cachexia

2014

cachexia exercise AICAR.
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