Author: Oscar Castellani

0000000000953417

AUTHOR

Oscar Castellani

Encapsulation de la lutéine et du DHA sous forme d’émulsions sèches : intérêt pour les pathologies rétiniennes

International audience

Bioavailability of dietary omega-3 DHA and lutein for the retina: results from a preclinical study in mini-pigs with encapsulated nutrients

Purpose: Epidemiological studies support the hypothesis that dietary omega-3 long chain polyunsaturated fatty acids and carotenoids prevent from Age-related Macular Degeneration (AMD). AREDS2 failed to find benefits of omega-3 supplementation on the progression to advanced AMD. However, lower risk progression was reported in AMD patients of the NAT2 study whom omega-3 incorporation in red blood cells and plasma was the highest. Our purpose was to test whether feeding mini-pigs with encapsulated docosahexaenoic acid (DHA) and lutein would promote the bioavailability of the nutrients in plasma and tissues including the retina. Methods: Microparticles containing lutein and DHA were formed by s…

research product

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