0000000000955100
AUTHOR
Gian Paolo Rossi
Prospective appraisal of the prevalence of primary aldosteronism in hypertensive patients presenting with atrial flutter or fibrillation (PAPPHY Study): rationale and study design
Primary aldosteronism (PA) is the most common endocrine form of hypertension and may carry an increased risk of atrial flutter or fibrillation (AFF). The primary goal of this multicentre cohort study is thus to prospectively establish the prevalence of PA in consecutive hypertensive patients referred for lone (non-valvular), paroxysmal or permanent AFF. Secondary objectives are to determine: (1) the predictors of AFF in patients with PA; (2) the rate of AFF recurrence at follow-up after specific treatment in the patients with PA; (3) the effect of AFF that can increase atrial natriuretic peptide via the atrial stretch and thereby blunt aldosterone secretion, on the aldosterone-to-renin rati…
The Footprints of a “Mastodon”: How a Decentralized Architecture Influences Online Social Relationships
Decentralized online social networks (DOSNs) have recently emerged as a viable solution to preserve the users' privacy and ensure higher users' control over the contents they publish. However, little is known about the backlashes that the decentralized organization and management of these platforms may have on the overlaid social network. This paper fills the gap. Specifically, we investigate how a decentralized architecture based on distributed servers impacts the structure of the users' neighborhood and their ego-networks. Our analysis relies on social data gathered from the decentralized micro-blogging platform Mastodon, the newest and fastest-growing decentralized alternative to Twitter…