0000000000964127
AUTHOR
Gabriel Laurent
showing 3 related works from this author
In Vitro Arrhythmia Generation by Mild Hypothermia - a Pitchfork Bifurcation Type Process
2015
International audience; The neurological damage after cardiac arrest (CA) constitutes a big challenge of hospital discharge. The therapeutic hypothermia (34°C-32°C) has shown its benefit to reduce cerebral oxygen demand and improve neurological outcomes after the cardiac arrest. However, it can have many adverse effects, among them the cardiac arrhythmia generation represents an important part (up to 34%, according different clinical studies). Monolayer cardiac culture is prepared with cardiomyocytes from new-born rat directly on the multi-electrodes array, which allows acquiring the extracellular potential of the culture. The temperature range is 37°C - 30°C - 37°C, representing the coolin…
Dynamical analysis for an in vitro model signal
2014
International audience
In vitro simulation of spiral waves in cardiomyocyte networks using multi-electrode array technology
2009
International audience; We aimed thus to provide new insights into the cellular origin of the fibrillation phenomenon by exploring the impulse propagation between cardiac myocytes in confluent monolayers of cultured cardiomyocytes (CM),