0000000000964216
AUTHOR
Hervé Cadiou
showing 5 related works from this author
Plasticity in the olfactory system: modulation by the odorant environment and diet
2015
As the primary neuronal element in the olfactory system, olfactory sensory neurons (OSNs) are responsible for detecting odor molecules, transforming chemical information to electrical signals and sending these signals to the brain. Being exposed to the environment, their lifetime is limited. The olfactory epithelium has the remarkable ability to regenerate sensory neurons throughout life. There is little data showing the effects of the environment, such as odorant exposure, on the properties of OSNs. Similarly, knowledge on the modulation by the physiological state of the animal (i.e. nutritional status) is limited. The long-term goal of our group is to investigate how the OSNs function dur…
Psychobiological effects of perinatal exposure to odorants in mice. Part II: Behavioural alteration
2010
Early exposure to odorants pre-, post- or transnatally is known to. result in a decreased avoidance or increased preference for these. odorants in mammals. There are also indications that olfactory sensitivity. for these odorants can be affected. We exposed C57-Bl/6. mice of Mor23-GFP and M71-GFP lines to lyral (LY) or acetophenone. (AC), respectively, either transnatally through the water of the. mother (1*10-5 M) or postnatally in air for 1 hr per day (20 ll pure). Animals were weaned on postnatal day 20 (P20), and 3 tests were. performed:. 1) A 3-min exploration test on P20 in a rectangular arena presenting. LY and AC under a wire mesh to measure the time spent in each. half of the arena…
Psychobiological effects of perinatal exposure to odorants in mice. Part II: Behavioural alterations
2010
National audience
Morphological and molecular changes in mouse olfactory epithelium following postnatal odorant exposures
2011
Morphological and molecular changes in mouse olfactory epithelium following postnatal odorant exposures. 10. annual meeting of the french neuroscience society
Postnatal odorant exposure induces peripheral olfactory plasticity at the cellular level
2014
Mammalian olfactory sensory neurons (OSNs) form the primary elements of the olfactory system. Inserted in the olfactory mucosa lining of the nasal cavity, they are exposed to the environment and their lifespan is brief. Several reports say that OSNs are regularly regenerated during the entire life and that odorant environment affects the olfactory epithelium. However, little is known about the impact of the odorant environment on OSNs at the cellular level and more precisely in the context of early postnatal olfactory exposure. Here we exposed MOR23-green fluorescent protein (GFP) and M71-GFP mice to lyral or acetophenone, ligands for MOR23 or M71, respectively. Daily postnatal exposure to …