0000000000965409

AUTHOR

José M. Romero

showing 3 related works from this author

Re: The Clinical Impact of Bacteremia on Outcomes in Elderly Patients with Pyelonephritis or Urinary Sepsis: A Prospective Multicenter Study

2018

Background Bacteremia is common in severe urinary infections, but its influence on the outcomes is not well established. The aim of this study was to assess the association of bacteremia with outcomes in elderly patients admitted to hospital with pyelonephritis or urinary sepsis. Methods This prospective muticenter observational study was conducted at 5 Spanish hospitals. All patients aged >65 years with pyelonephritis or urinary sepsis admitted to the departments of internal medicine and with urine and blood cultures obtained at admission to hospital were eligible. Transfer to ICU, length of hospital stay, hospital mortality and all cause 30-day mortality in bacteremic and non-bacteremic g…

Bacterial DiseasesMaleMultivariate analysisPhysiologylcsh:MedicineBacteremiaUrineUrinePathology and Laboratory MedicineElderly0302 clinical medicineMedicine and Health Sciences030212 general & internal medicineProspective Studieslcsh:ScienceProspective cohort studyAged 80 and overMultidisciplinaryPyelonephritisHospitalsBody FluidsInfectious DiseasesBloodCohortUrinary Tract InfectionsFemaleAnatomyResearch Articlemedicine.medical_specialtyUrologyUrinary systemMEDLINESepsis03 medical and health sciencesSigns and SymptomsDiagnostic MedicineSepsisInternal medicinemedicineHumansAgedSeptic shockbusiness.industrylcsh:RBiology and Life Sciencesmedicine.diseaseHealth Care030228 respiratory systemMulticenter studyHealth Care FacilitiesGeriatricsAge GroupsBacteremiaPeople and PlacesPopulation Groupingslcsh:QbusinessJournal of Urology
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Inadequate empirical antimicrobial treatment in older people with bacteremic urinary tract infection who reside in nursing homes: A multicenter prosp…

2019

AIM The aim of the study was to determine the rate of inadequate empirical antimicrobial treatment in older nursing home residents with bacteremic urinary tract infection and its influence on prognosis. METHODS We carried out a multicentric prospective observational study in five Spanish hospitals. Patients aged >65 years with pyelonephritis or urinary sepsis with bacteremia were included. Clinical characteristics, the percentage of inadequate empirical antibiotic treatment, length of hospital stay and mortality were evaluated. RESULTS A total of 181 patients, 54.7% women, were included in the study, and 35.9% of the patients came from nursing homes. These patients had higher percentages of…

Malemedicine.medical_specialtyMultivariate analysismedicine.drug_classUrinary systemAntibioticsBacteremiaInappropriate PrescribingSepsisInternal medicinemedicineHomes for the AgedHumansProspective StudiesAgedAged 80 and overbusiness.industrymedicine.diseaseAntimicrobialAnti-Bacterial AgentsNursing HomesSpainBacteremiaUrinary Tract InfectionsObservational studyFemaleNursing homesbusinessGeriatricsgerontology internationalReferences
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Evolutionary Analysis of DELLA-Associated Transcriptional Networks

2017

DELLA proteins are transcriptional regulators present in all land plants which have been shown to modulate the activity of over 100 transcription factors in Arabidopsis, involved in multiple physiological and developmental processes. It has been proposed that DELLAs transduce environmental information to pre-wired transcriptional circuits because their stability is regulated by gibberellins (GAs), whose homeostasis largely depends on environmental signals. The ability of GAs to promote DELLA degradation coincides with the origin of vascular plants, but the presence of DELLAs in other land plants poses at least two questions: what regulatory properties have DELLAs provided to the behavior of…

0301 basic medicineevo–devoChlamydomonas reinhardtiiPlant ScienceBiologylcsh:Plant culturePhyscomitrella patensGene co-expression networks03 medical and health sciencesTranscriptional regulationArabidopsisBotanyTranscriptional regulationBIOQUIMICA Y BIOLOGIA MOLECULARArabidopsis thalianalcsh:SB1-1110Transcription factorIntegrative molecular systems biologyOriginal ResearchEvo-devofood and beveragesPlant signalingbiology.organism_classificationCell biologyGENETICA030104 developmental biologyEvolutionary developmental biologyFunction (biology)
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