0000000000965431

AUTHOR

Hamann Gerhard F

showing 2 related works from this author

Holter-electrocardiogram-monitoring in patients with acute ischaemic stroke (Find-AFRANDOMISED): an open-label randomised controlled trial.

2017

Summary Background Atrial fibrillation is a major risk factor for recurrent ischaemic stroke, but often remains undiagnosed in patients who have had an acute ischaemic stroke. Enhanced and prolonged Holter-electrocardiogram-monitoring might increase detection of atrial fibrillation. We therefore investigated whether enhanced and prolonged rhythm monitoring was better for detection of atrial fibrillation than standard care procedures in patients with acute ischaemic stroke. Methods Find-AF randomised is an open-label randomised study done at four centres in Germany. We recruited patients with acute ischaemic stroke (symptoms for 7 days or less) aged 60 years or older presenting with sinus rh…

medicine.medical_specialtyIntention-to-treat analysisbusiness.industryAtrial fibrillation030204 cardiovascular system & hematologymedicine.disease3. Good healthlaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawInternal medicineClinical endpointCardiologyMedicineSinus rhythmNeurology (clinical)cardiovascular diseasesRisk factorbusinessStroke030217 neurology & neurosurgeryAtrial flutterThe Lancet. Neurology
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Diagnostic accuracy of plasma glial fibrillary acidic protein for differentiating intracerebral hemorrhage and cerebral ischemia in patients with sym…

2011

Abstract BACKGROUND Glial fibrillary acidic protein (GFAP) is a biomarker candidate indicative of intracerebral hemorrhage (ICH) in patients with symptoms of acute stroke. GFAP is released rapidly in the presence of expanding intracerebral bleeding, whereas a more gradual release occurs in ischemic stroke. In this study the diagnostic accuracy of plasma GFAP was determined in a prospective multicenter approach. METHODS Within a 1-year recruitment period, patients suspected of having acute (symptom onset <4.5 h before admission) hemispheric stroke were prospectively included into the study in 14 stroke centers in Germany and Switzerland. A blood sample was collected at admission, and …

AdultMalemedicine.medical_specialtyClinical BiochemistryIschemiaBrain IschemiaDiagnosis DifferentialInterquartile rangeInternal medicineGlial Fibrillary Acidic ProteinmedicineHumansIn patientcardiovascular diseasesProspective StudiesProspective cohort studyStrokeAgedCerebral HemorrhageIntracerebral hemorrhageImmunoassayAutoanalysisGlial fibrillary acidic proteinbiologybusiness.industryBiochemistry (medical)Electrochemical TechniquesMiddle Agedmedicine.diseaseSurgeryStrokeAcute DiseaseLuminescent MeasurementsCardiologybiology.proteinBiomarker (medicine)FemalebusinessBiomarkersClinical chemistry
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