0000000000965593

AUTHOR

Ulrike Soeling

showing 2 related works from this author

Impact of prognostic factors on long-term outcomes in metastatic breast cancer (MBC) patients (pts) receiving bevacizumab (B) plus paclitaxel as firs…

2014

e12007 Background: B combined with chemotherapy (CT) significantly improves progression-free survival (PFS) and response rate (RR) vs CT alone in the first-line treatment of HER2-negative MBC. In a...

Response rate (survey)OncologyCancer Researchmedicine.medical_specialtyChemotherapyBevacizumabbusiness.industryFirst linemedicine.medical_treatmentMedizinmedicine.diseaseMetastatic breast cancerSurgerychemistry.chemical_compoundOncologyPaclitaxelchemistryInternal medicinemedicineLong term outcomesCytotoxic T cellskin and connective tissue diseasesbusinessneoplasmsmedicine.drugJournal of Clinical Oncology
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Efficacy and safety of irinotecan-based chemotherapy for advanced colorectal cancer outside clinical trials: an observational study.

2010

Background: This prospective observational study in typical community-based outpatient clinics evaluated the efficacy and toxicity of weekly and biweekly irinotecan-based chemotherapies and their compatibility depending on age. Methods: 601 patients with advanced or metastatic colorectal cancer receiving first-, second-, or third-line irinotecanbased therapy were regularly analyzed for response and toxicity until the end of therapy. Results: The median age was 65 (28–87) years, approximately one-third of the patients were ≥70 years old. Of all patients, 405 were treated weekly and 68 biweekly. Median overall survival (OS) for first-line therapy was 26.5 months for the <70-year-old patients …

OncologyMaleCancer ResearchOrganoplatinum CompoundsColorectal cancermedicine.medical_treatmentLeucovorinAntineoplastic Combined Chemotherapy ProtocolsOutpatient clinicProspective StudiesAged 80 and overClinical Trials as TopicAge FactorsHematologyGeneral MedicineMiddle AgedCombined Modality TherapyTumor BurdenSurvival RateTreatment OutcomeOncologyChemotherapy AdjuvantDisease ProgressionFemaleFluorouracilColorectal Neoplasmsmedicine.drugAdultmedicine.medical_specialtyCombination therapyDrug-Related Side Effects and Adverse ReactionsMedizinische Fakultät -ohne weitere Spezifikation--AdenocarcinomaIrinotecanDrug Administration ScheduleAdvanced colorectal cancerInternal medicinemedicineHumansddc:610AgedNeoplasm StagingChemotherapybusiness.industrymedicine.diseaseClinical trialIrinotecanObservational studyCamptothecinbusinessOnkologie
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