0000000000968620

AUTHOR

Hanna Siiskonen

showing 2 related works from this author

The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

2022

This update and revision of the international guideline for urticaria was developed following the methods recommended by Cochrane and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) working group. It is a joint initiative of the Dermatology Section of the European Academy of Allergology and Clinical Immunology (EAACI), the Global Allergy and Asthma European Network (GALEN) and its Urticaria and Angioedema Centers of Reference and Excellence (UCAREs and ACAREs), the European Dermatology Forum (EDF; EuroGuiDerm), and the Asia Pacific Association of Allergy, Asthma and Clinical Immunology with the participation of 64 delegates of 50 national and international soci…

medicine.medical_specialtyEvidence-based practicehivesmedia_common.quotation_subjectImmunologyeducation610DermatologyAngioedema/diagnosis030207 dermatology & venereal diseases03 medical and health sciencesurticaria0302 clinical medicineQuality of lifeExcellenceimmune system diseasesevidence-basedparasitic diseasesmedicinePrevalenceImmunology and Allergymedia_common.cataloged_instanceHumansitchEuropean unionskin and connective tissue diseaseswhealAsthmamedia_commonAngioedemabusiness.industryangioedemaConsensus conferenceGUIDELINES ; angioedema ; consensus ; evidence2̆010based ; hives ; itch ; mast cell ; urticaria ; whealGuidelinemedicine.diseaseAsthma3. Good healthddc:030228 respiratory systemconsensusFamily medicineChronic DiseaseQuality of LifeUrticaria/diagnosismedicine.symptombusinessmast cell600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit
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The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3 + and CD8 +) and tumor-associated macrophages in early HER2 + breast canc…

2023

Purpose In HER2-positive (HER2 +) breast cancer, tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs) may influence the efficacy of the HER2-antibody trastuzumab and the patient’s outcome. In this HER2 + patient cohort, our aim was to study the numbers of FoxP3 + regulatory TILs and CD8 + cytotoxic TILs, their correlations with CD68 + and CD163 + TAMs, and the prognostic and predictive value of the studied factors. Methods We evaluated 139 non-metastatic HER2 + breast cancer patients operated between 2001 and 2008. The FoxP3+TIL count (FoxP3+TILs) was assessed using the hotspot method, and the CD8 + TIL count (CD8+mTILs) utilizing a digital image analysis from invas…

breast cancerkasvaimetrintasyöpätumor-associated macrophagestumor-infiltrating lymphocytessyöpätauditlymfosyytitmakrofagit
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