0000000000970810
AUTHOR
Mariann Arnyasi
showing 8 related works from this author
Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gene in clini…
2016
Background Clinical mastitis is an inflammation of the mammary gland and causes significant costs to dairy production. It is unfavourably genetically correlated to milk production, and, thus, knowledge of the mechanisms that underlie these traits would be valuable to improve both of them simultaneously through breeding. A quantitative trait locus (QTL) that affects both clinical mastitis and milk production has recently been fine-mapped to around 89 Mb on bovine chromosome 6 (BTA6), but identification of the gene that underlies this QTL was not possible due to the strong linkage disequilibrium between single nucleotide polymorphisms (SNPs) within this region. Our aim was to identify the gen…
"Islands of divergence" in the Atlantic cod genome represent polymorphic chromosomal rearrangements
2016
- In several species genetic differentiation across environmental gradients or between geographically separate populations has been reported to center at “genomic islands of divergence,” resulting in heterogeneous differentiation patterns across genomes. Here, genomic regions of elevated divergence were observed on three chromosomes of the highly mobile fish Atlantic cod (Gadus morhua) within geographically fine-scaled coastal areas. The “genomic islands” extended at least 5, 9.5, and 13 megabases on linkage groups 2, 7, and 12, respectively, and coincided with large blocks of linkage disequilibrium. For each of these three chromosomes, pairs of segregating, highly divergent alleles were id…
MOESM2 of Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gen…
2016
Additional file 2: Table S2. Primer sequences used for the reverse transcription qPCR (RT-qPCR).
MOESM3 of Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gen…
2016
Additional file 3: Figure S1. Further description of the procedure for estimating DBP protein levels. Detailed description of the protocol for estimating the DBP levels in serum from 50 NR cows. Figure S1 gives a schematic explanation of vitamin D3 metabolism.
MOESM6 of Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gen…
2016
Additional file 6: Table S5. Results for General Linear Model (GLM) analyses of effect of rs110675140 genotype on DBP, ALB, 25(OH)D2, 25(OH)D3 and total 25(OH)D; free 25(OH)D2, 25(OH)D3 and total 25(OH)D; bioavailable (i.e., free and ALB-bound) 25(OH)D2, 25(OH)D3 and total 25(OH)D; DBP-bound total 25(OH)D; and ALB-bound total 25(OH)D serum concentrations. Detailed results of GLM analyses of genotype effect on several serum protein levels in 50 NR cows.
MOESM5 of Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gen…
2016
Additional file 5: Table S4. Results for single marker association analyses of CM1, CM4, CM6, kg milk, kg protein and kg fat on imputed full sequence data. Positions in basepairs, rs numbers, â log10(p value), minor allele frequency, SNP effects, alleles, putative consequences of the variants on the protein sequence and nearest gene for the imputed full sequence SNPs. The file contains six sheets, one for each tested trait.
MOESM1 of Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gen…
2016
Additional file 1: Table S1. SNP genotype, pregnancy status, age, lactation number and lactation status for the cows used for analyses of protein concentrations and ligand binding.
MOESM4 of Fine mapping of a QTL on bovine chromosome 6 using imputed full sequence data suggests a key role for the group-specific component (GC) gen…
2016
Additional file 4: Table S3. Results for single marker association analyses of seven mastitis traits and five milk traits on BTA6 markers from the Illumina BovineHD BeadChip. rs numbers, positions in basepairs, â log10(p value), SNP effects and alleles for all markers on BTA6 on the Illumina BovineHD BeadChip. The file contains twelve sheets, one for each trait.