Study of left ventricle ejection fraction and natriuretic peptides in patients with heart failure treated with systemic medical ozone.

Heart Failure (HF) is a prevalent disease and is a frequent reason for consultation. It is a complex entity that presents multiple pathophysiological aspects, and it is sometimes difficult to establish an adequate diagnosis, since its signs and symptoms may overlap with those of other diseases. For a better diagnosis and control of this pathology, it is currently essential to follow up through echocardiography and the determination of natriuretic peptides, since this increase significantly in patients with heart failure, having a negative predictive value for these patients. For this reason, we set out to study the effects of rectal ozone treatment on cardiac contractility and natriuretic p…