0000000000976812

AUTHOR

Ali S. Khashan

showing 2 related works from this author

67 The effect of hypertensive disorders of pregnancy on the risk of attention-deficit/hyperactivity disorder in the offspring

2016

Introduction Attention-deficit/hyperactivity disorder (ADHD) is a frequent neurodevelopmental disorder. Inadequate placentation as a result of hypertensive disorders of pregnancy has been proposed to be a central mechanism of fetal neurodevelopmental comprise. Recently it has been shown that pre-eclampsia increases the risk of ADHD [Mann and McDermott, 2011] . Objectives We examined the association between hypertensive disorders of pregnancy and ADHD and behavioural difficulties among 7-year old children. We also examined whether circulating factors in serum from women with a HDP alter early patterns of fetal neural growth. Methods The study cohort consisted of 13,192 children (weighted = 1…

medicine.medical_specialtyPregnancyEclampsiabusiness.industryObstetricsOffspring05 social sciencesObstetrics and Gynecologymedicine.diseasePreeclampsia03 medical and health sciences0302 clinical medicineEndocrinologyNeurodevelopmental disorderInternal medicineCohortInternal MedicineMedicineGestationAttention deficit hyperactivity disorder0501 psychology and cognitive sciencesbusiness030217 neurology & neurosurgery050104 developmental & child psychologyPregnancy Hypertension: An International Journal of Women's Cardiovascular Health
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The Effect of Hypertensive Disorders of Pregnancy on the Risk of ADHD in the Offspring

2017

Objective: Evidence suggests that perinatal factors may contribute to the development of ADHD. Our objective was to examine the association between hypertensive disorders of pregnancy (HDP) and ADHD, and behavioral difficulties among 7-year-old children. Method: The study cohort consisted of 13,192 children (weighted = 13,500) who participated in the Millennium Cohort Study (MCS) at age 7. HDP (raised blood pressure, preeclampsia, eclampsia, and toxemia) were reported by mothers 9 months postdelivery. ADHD was reported by parents at age 7 years. Weighted logistic regression models were used to assess the association. Results: In all, 1,069 (7.9%) women reported HDP and 166 (1.2%) children h…

AdultMaleAdolescentOffspringCohort StudiesYoung Adult03 medical and health sciences0302 clinical medicinePregnancyRisk Factorsmental disordersOdds RatioDevelopmental and Educational PsychologymedicineHumans0501 psychology and cognitive sciencesChildAssociation (psychology)Pregnancy05 social sciencesHypertension Pregnancy-Inducedmedicine.diseaseClinical PsychologyLogistic ModelsAttention Deficit Disorder with HyperactivityFemalePsychology030217 neurology & neurosurgery050104 developmental & child psychologyClinical psychologyJournal of Attention Disorders
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