0000000000980877

AUTHOR

Lorena Puchades

showing 2 related works from this author

Cytomegalovirus reactivation in liver transplant recipients due to hepatitis C cirrhosis is associated with higher cardiovascular risk - an observati…

2017

The association between cytomegalovirus (CMV) reactivation and cardiovascular risk has been reported in solid organ transplant populations; however, it has yet to be assessed in liver transplantation (LT). We aim to evaluate whether CMV reactivation is associated with cardiovascular events (CVE) in HCV-LT patients. LT patients (2010 and 2014) due to HCV cirrhosis were included. Clinically significant CMV (CS-CMV) was defined as viral load (VL) >5000 copies/ml, need of therapy or CMV disease. Baseline variables and endpoint measures (CVE, survival, severe recurrent hepatitis C, de novo tumors, and diabetes) were collected. One hundred and forty patients were included. At LT, a history of AHT…

Liver CirrhosisMalemedicine.medical_specialtyCirrhosismedicine.medical_treatmentCongenital cytomegalovirus infectionCytomegalovirus030230 surgeryLiver transplantationGastroenterology03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusInternal medicinemedicineHumansAgedProportional Hazards ModelsRetrospective StudiesImmunosuppression TherapyTransplantationProportional hazards modelbusiness.industryvirus diseasesRetrospective cohort studyHepatitis CMiddle AgedViral Loadmedicine.diseaseHepatitis CTissue DonorsLiver TransplantationCardiovascular DiseasesCytomegalovirus Infections030211 gastroenterology & hepatologyFemalebusinessViral loadGlomerular Filtration RateTransplant international : official journal of the European Society for Organ Transplantation
researchProduct

Framingham score, renal dysfunction, and cardiovascular risk in liver transplant patients

2015

Cardiovascular (CV) events represent major impediments to the long-term survival of liver transplantation (LT) patients. The aim of this study was to assess whether the Framingham risk score (FRS) at transplantation can predict the development of post-LT cardiovascular events (CVEs). Patients transplanted between 2006 and 2008 were included. Baseline features, CV risk factors, and CVEs occurring after LT (ischemic heart disease, stroke, heart failure, de novo arrhythmias, and peripheral arterial disease) were recorded. In total, 250 patients (69.6% men) with a median age of 56 years (range, 18-68 years) were included. At transplantation, 34.4%, 34.4%, and 33.2% of patients, respectively, ha…

AdultMalemedicine.medical_specialtyTime FactorsAdolescentmedicine.medical_treatmentRenal functionKaplan-Meier EstimateLiver transplantationKidneyRisk AssessmentGastroenterologyYoung AdultRisk FactorsInternal medicinemedicineHumansAgedProportional Hazards ModelsRetrospective StudiesTransplantationUnivariate analysisFramingham Risk ScoreHepatologybusiness.industryProportional hazards modelHazard ratioHepatitis CMiddle Agedmedicine.diseaseHepatitis CTransplant RecipientsLiver TransplantationSurgeryTransplantationLogistic ModelsTreatment OutcomeCardiovascular DiseasesSpainMultivariate AnalysisFemaleKidney DiseasesSurgerybusinessGlomerular Filtration Rate
researchProduct