0000000000981065
AUTHOR
C Sannino
Dissemination of oenological yeasts through bird migration in Sicily.
The composition of yeast communities on shown to be dependent on several factors, including geographical location of the vineyard, type of soil, age of the vineyard, grapevine variety and harvesting technique. Moreover, insects and birds were in part responsible for the dissemination of fermentative yeasts during their feeding (Francesca et al, 2009). In order to evaluate the dissemination of fermenting yeasts, migrating and vineyard inhabiting birds were caught and ringed in four experimental sites: “Riserva Naturale Integrale Lago Preola e Ghorghi Tondi” (Mazara del Vallo, TP) and the Sicilian islands of Lampedusa, Ustica and Linosa. The last sites represent important stop-over for migrat…
Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial
Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50â75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2â3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…