0000000000985540

AUTHOR

Leonardo Orazi

0000-0002-4507-0518

showing 2 related works from this author

Cell and Tissue Response to Modified by Laser-induced Periodic Surface Structures Biocompatible Materials for Dental Implants

2016

The use of femtosecond laser-induced periodic surface structures (LIPSS) for dental implants surface modification for improving cell adhesion and proliferation is reported. Results demonstrated higher response of cells on modified surface compared to untreated ones.

Surface (mathematics)0209 industrial biotechnologyMaterials scienceCell02 engineering and technology021001 nanoscience & nanotechnologyBiocompatible materialLaserlaw.invention020901 industrial engineering & automationmedicine.anatomical_structurelawAtomic and Molecular PhysicsFemtosecondElectronicmedicineSurface modificationOptical and Magnetic Materialsand OpticsElectrical and Electronic EngineeringAtomic and Molecular Physics and Optics; Electronic Optical and Magnetic Materials; Electrical and Electronic Engineering0210 nano-technologyCell adhesionBiomedical engineering
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Cell and tissue response to nanotextured Ti6Al4V and Zr implants using high-speed femtosecond laser-induced periodic surface structures

2019

In this paper, the effect of femtosecond laser nanotexturing of surfaces of Ti6Al4V and Zr implants on their biological compatibility is presented and discussed. Highly regular and homogeneous nanostructures with sub-micrometer period were imprinted on implant surfaces. Surfaces were morphologically and chemically investigated by SEM and XPS. HDFa cell lines were used for toxicity and cell viability tests, and subcutaneous implantation was applied to characterize tissue response. HDFa proliferation and in vivo experiments evidenced the strong influence of the surface topography compared to the effect of the surface elemental composition (metal or alloy). The effect of protein adsorption fro…

Materials scienceNanostructureSurface PropertiesBiomedical EngineeringPharmaceutical ScienceMedicine (miscellaneous)chemistry.chemical_elementBioengineering02 engineering and technologyOsseointegrationCell proliferation; Femtosecond laser; Fluorescence; HR-LIPSS; Nanotexturing; Cell Differentiation; Humans; Lasers; Nanostructures; Osseointegration; Osteoblasts; Osteogenesis; Surface Properties; Titanium; Zirconium; Prostheses and ImplantsFluorescencelaw.invention03 medical and health sciencesX-ray photoelectron spectroscopylawOsseointegrationOsteogenesisAlloysHumansGeneral Materials ScienceCell proliferation030304 developmental biologyTitanium0303 health sciencesOsteoblastsLasersTitanium alloyCell DifferentiationProstheses and Implants021001 nanoscience & nanotechnologyLaserNanotexturingNanostructuresFemtosecond laserchemistryFemtosecondBiophysicsMolecular MedicineHR-LIPSSZirconiumNanotexturingCell proliferationFluorescenceHR-LIPSSFemtosecond laser0210 nano-technologyTitaniumProtein adsorption
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