0000000000986976
AUTHOR
M Maggio
MAGNESIUM AND ANABOLIC HORMONES IN OLDER MEN
Optimal nutritional and hormonal statuses are determinants of successful age-ing. The age associated decline in anabolic hormones such as testosterone and insulin-like growth factor 1 (IGF-1) is a strong predictor of metabolic syn-drome, diabetes and mortality in older men. Studies have shown that magne-sium intake affects the secretion of total IGF-1 and increase testosterone bioactivity. This observation suggests that magnesium can be a modulator of the anabolic ⁄ catabolic equilibrium disrupted in the elderly people. However, the relationship between magnesium and anabolic hormones in men has not been investigated. We evaluated 399 ‡65-year-old men of CHIANTI in a study population repres…