Clinical and Functional Outcome After Abdominal Wall Incisional Hernia Repair: Evaluation of Quality-of-Life Improvement and Comparison of Assessment…

2019

Background Hernias severely impact patient quality of life (QoL), and 80% of patients need surgical operation. The primary outcome of the study is to assess improvements in balance, posture and deambulation after abdominal hernia repair. Moreover, the study investigated the improvement in the postoperative QoL. Methods Patients operated at the Policlinico “Paolo Giaccone” at Palermo University Hospital between June 2015 and June 2017 were identified in a prospective database. The functional outcome measures and QoL assessment scales used were numeric rating scale for pain, performance-oriented mobility assessment (POMA) scale, Quebec back pain disability scale, center of gravity (barycenter…

Terminal or truncal ligation of the inferior thyroid artery during thyroidectomy? A prospective randomized trial.

2016

Abstract Introduction Thyroidectomy is a common procedure in general and endocrine surgery. The technique of ligation of inferior thyroid artery (ITA) has been invoked as a possible cause of appearance of postoperative hypocalcemia. Methods We performed a prospective randomized study involving 184 patients undergoing total thyroidectomy to evaluate the differences of truncal ligation versus distal ligation of ITA in terms of postoperative hypocalcemia, vocal fold palsy, voice and swallowing impairment. The patients were divided into group A (trunk ligation of ITA) and group B (terminal branches ligation of ITA). Results We evaluated postoperative PTH and calcemia (immediate, 6 and 12 months…

Vinflunine in Metastatic Urothelial Carcinoma of the Bladder in Progression after a Platinum-Containing Regimen

2019

<b><i>Background:</i></b> Vinflunine is a microtubule inhibitor of the vinca alkaloid class approved for the treatment of urothelial bladder carcinoma after a platinum-containing regimen. <b><i>Methods:</i></b> To evaluate the effectiveness of vinflunine, we enrolled 80 subjects with a histologically confirmed diagnosis of metastatic urothelial bladder carcinoma that had previously undergone chemotherapy with a platinum-containing regimen and had measurable lesions according to the Response Evaluation Criteria in Solid Tumors (RECIST). The patients (<i>n</i> = 80) received vinflunine (Javlor®) every 3 weeks at 320 mg/m<sup>2&…

<p>Nab-paclitaxel in pretreated metastatic breast cancer: evaluation of activity, safety, and quality of life</p>

2019

Objective Metastatic breast cancer (MBC) is an incurable disease; the treatment of this disease prolongs survival, improving the quality of life (QoL) with a balance between efficacy and toxicity of the treatment. In recent years, treatment with nab-paclitaxel has improved the already known antitumor activity of conventional paclitaxel, in terms of increased efficacy and better tolerability. The aim of this study was to evaluate nab-paclitaxel in Italian patients with MBC. Methods We conducted a retrospective analysis of 90 patients with histologically confirmed diagnosis of MBC. To evaluate the efficacy of nab-paclitaxel, overall survival (OS), progression-free survival (PFS), and overall …

Deep SSI after mesh-mediated groin hernia repair: Management and outcome in an Emergency Surgery Department

2017

Aim. Mesh-mediated groin hernia repair is considered the goldstandard procedure. It has low recurrence rate. Rarely a deep Surgical Site Infection (SSI) is seen when a synthetic prosthesis is used. Case report. We describe a rare case of bilateral deep SSI after mesh- mediated groin hernia repair. Diagnosis was performed through the physical examination and radiological exams. Microbiological samples identified a methicillin-resistant Staphylococcus aureus responsible of the infection. Target therapy was performed and re-operation performed in order to remove the infected prosthesis and to apply a biological one to create the fibrous scaffold. During follow-up time, right side recurrence wa…

DIFFERENZE PROGNOSTICHE NEL CARCINOMA COLO-RETTALE TRATTATO IN CONDIZIONI DI ELEZIONE E DI URGENZA

2004

RUOLO DELLA VIDEOLAPAROSCOPIA NELLE URGENZE PELVICHE: NOSTRA ESPERIENZA

2004

DIAGNOSI PRECOCE ED INTERVENTO D’URGENZA NELLA COLECISTITE ACUTA ALITIASICA

2004

DIAGNOSI PRECOCE ED INTERVENTO D’URGENZA NELLA COLECISTITE ACUTA ALITIASICA.

IL PARAGANGLIOMA: PRESENTAZIONE DI UN CASO CLINICO.

2004

LINFOADENOPATIE PERIFERICHE: QUANDO L’EXERESI A SCOPO BIOPTICO?

2004

GLI EMATOMI RETROPERITONEALI POST-TRAUMATICI

2004

Malattia di Crohn: diagnosi e trattamento in urgenza.

2004

Studio clinico sulla profilassi antibiotica "Ultra- Short term" in chirurgia tiroidea con amoxicillina-acido clavulanico.

2004

LE EMORRAGIE DIGESTIVE DEL TRATTO SOVRAMESOCOLICO: OSSERVAZIONE DI ALCUNI CASI CLINICI

2004

COMPLICANZE BILIARI DEL TRATTAMENTO CHIRURGICO CONSERVATIVO DELL’IDATIDOSI EPATICA

2004

Studio di Fase II con Gemcitabina + oxaliplatino in combinazione nel trattamento delle neoplasie delle vie biliari, pancreas e colecisti in fase meta…

2007

Studio di Fase II con Gemcitabina + oxaliplatino in combinazione nel trattamento delle neoplasie delle vie biliari, pancreas e colecisti in fase metastatica.

Ruolo della videolaparoscopia nei pazienti con ischemia intestinale manifesta o sospetta.

2004

Ruolo della videolaparoscopia nei pazienti con ischemia intestinale manifesta o sospetta..