Triazolopyridines. Part 9. The synthesis of7-amino(1,2,3)triazolo(1,5-a)pyridines

Abstract Regiospecific lithiation of (1,2,3) triazolo(1,5-a)pyridines (1) and (4) with subsequent reaction with styryl azide gave small yields of the 7-aminotriazolopyridines (6) and (7). A longer larger scale synthesis of compounds (6) and (7) is described giving overall yields of 17 and 25%, starting from 2-amino-6-methyl (9) or 2-amino-6-ethyl pyridine (19).