0000000000994188
AUTHOR
Konstantinos Prokopidis
Additional file 1 of Medium-chain triglycerides may improve memory in non-demented older adults: a systematic review of randomized controlled trials
Additional file 1: Table S1. Search terms employed in the literature search.
Medium-chain triglycerides may improve memory in non-demented older adults: a systematic review of randomized controlled trials
Abstract Background Ketosis has been exploited for its neuroprotective impact and treatment of neurological conditions via ketone production. Exogenous medium-chain triglyceride (MCT) supplementation may induce nutritional ketosis. The aim of this systematic review is to explore the effects of MCTs on memory function in older adults without cognitive impairment. Methods A systematic literature search of PubMed, Cochrane Library, Scopus, and Web of Science was employed from inception until April 2022 for randomized controlled trials (RCTs) in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, investigating the impact of MCT oils on com…
Additional file 2 of Medium-chain triglycerides may improve memory in non-demented older adults: a systematic review of randomized controlled trials
Additional file 2: Table S2. Population, Intervention, Comparison, Outcomes and Study (PICOS) criteria for the inclusion of studies in the systematic review.
Effects of Creatine Supplementation on Brain Function and Health
While the vast majority of research involving creatine supplementation has focused on skeletal muscle, there is a small body of accumulating research which has focused on creatine and the brain. Preliminary studies indicate that creatine supplementation (and guanidinoacetic acid; GAA) has the ability to increase brain creatine content in humans. Further, creatine has shown some promise for attenuating symptoms of concussion, mild traumatic brain injury and depression but its effect on neurodegenerative diseases appears lacking. The purpose of this narrative review is to summarize the current body of research pertaining to creatine supplementation on total creatine and phophorylcreatine cont…