0000000001003515

AUTHOR

Ciancio A.

showing 2 related works from this author

Evolving clinical landscape of chronic hepatitis B: A multicenter Italian study

2009

The aim of the study was to evaluate the characteristics of chronic hepatitis B with special reference to the geographical origin of the patients and to the prevalence of HBeAg and viral and non-viral co-factors of liver disease. A cross-sectional multicenter survey was undertaken, which enrolled 1,386 HBsAg chronic carriers observed consecutively in 21 referral centers over a 6-month period. The prevalence of HBeAg in patients was 11%; the presence of HBeAg was associated independently with a younger age and co-infection with HIV. Anti-HDV, anti-HCV, or anti-HIV antibodies were detected in 8.1%, 6.5%, and 2%, respectively. However, among the patients first diagnosed during the study period…

MaleHBsAgvirusesHIV InfectionsAntibodies ViralHBeAgHepatitisLiver diseaseCHRONIC HEPATITIS B; HBsAg; epidemiology; GEOGRAPHICAL LANDSCAPEHBsAg0302 clinical medicine80 and overPrevalenceViralChronicAged 80 and over0303 health sciencesGeographyAge Factorsvirus diseasesHepatitis CHepatitis BMiddle AgedHepatitis BHepatitis D3. Good healthInfectious DiseasesHBeAgCirrhosisItalyMedicineepidemiology030211 gastroenterology & hepatologyFemaleHepatitis D virusHumanAdultHepatitis Viral HumanAdolescentCHRONIC HEPATITIS BAntibodies03 medical and health sciencesHepatitis B ChronicHDVVirologyCirrhosis HBeAg HDV Hepatitis B Adolescent Adult Age Factors Aged Aged 80 and over Antibodies Viral Cross-Sectional Studies Female Geography HIV HIV Infections Hepatitis B Chronic Hepatitis Viral Human Humans Italy Male Middle Aged Prevalence Virology Infectious DiseasesmedicineCirrhosis; HBeAg; HDV; Hepatitis B; Adolescent; Adult; Age Factors; Aged; Aged 80 and over; Antibodies Viral; Cross-Sectional Studies; Female; Geography; HIV; HIV Infections; Hepatitis B Chronic; Hepatitis Viral Human; Humans; Italy; Male; Middle Aged; Prevalence; Infectious Diseases; VirologyHumans030304 developmental biologyAgedHepatitisCirrhosibusiness.industryHIVmedicine.diseaseVirologydigestive system diseasesCross-Sectional StudiesGEOGRAPHICAL LANDSCAPEbusiness
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Treatment with tenofovir disoproxil fumarate or entecavir in chronic hepatitis B virus-infected patients with renal impairment: results from a 7-year…

2020

BackgroundLimited data exist regarding tenofovir disoproxil fumarate (TDF) safety and effectiveness in chronic hepatitis B virus-infected (CHB) patients with renal impairment (RI).AimsTo compare real-world data on renal safety and effectiveness of TDF vs entecavir (ETV) in CHB patients with moderate-to-severe RI.MethodsRetrospective, non-interventional, cohort study analysing medical records for TDF/ETV-treated CHB patients (54 European centres). Included patients experienced moderate-to-severe RI (creatinine clearance 20-60 mL/min [Cockcroft-Gault]) either before TDF/ETV initiation ('before' subgroup [baseline = treatment initiation]) or after TDF/ETV initiation ('after' subgroup [baseline…

MaleAdultmedicine.medical_specialtyGuanineTenofovirMEDLINEAntiviral AgentsVirus03 medical and health sciencesYoung Adult0302 clinical medicineHepatitis B ChronicRetrospective StudieInternal medicine80 and overHBVMedicineHumansPharmacology (medical)030212 general & internal medicineRenal InsufficiencyYoung adultAdult; Aged; Aged 80 and over; Antiviral Agents; Female; Guanine; Hepatitis B Chronic; Humans; Male; Middle Aged; Renal Insufficiency; Retrospective Studies; Tenofovir; Treatment Outcome; Young AdultChronicTenofovirAgedRetrospective StudiesAged 80 and overAntiviral AgentHepatologybusiness.industryGastroenterologyvirus diseasesRetrospective cohort studyEntecavirHepatitis BMiddle Agedmedicine.diseaseHepatitis BTreatment OutcomeCohort030211 gastroenterology & hepatologyFemalebusinessmedicine.drugHuman
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