0000000001007948

AUTHOR

F Fatuzzo

showing 3 related works from this author

Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatit…

2011

Transient elastography (TE) is adequate for a diagnosis of cirrhosis, but its accuracy for milder stages of fibrosis is much less satisfactory. The objective of this study was to compare the performance and the discordance rate of acoustic radiation force impulse (ARFI) and TE with liver biopsy in a cohort of chronic hepatitis C (CHC) patients.One hundred thirty-nine consecutive patients with CHC were enrolled in two tertiary centers, and evaluated for histological (Metavir score) and biochemical features. All patients underwent TE and ARFI.TE was unreliable in nine patients (6.5%), while in no cases (0%) were ARFI invalid measurements recorded (P=0.029). By area under receiver operating ch…

AdultLiver CirrhosisMalemedicine.medical_specialtyHepacivirusLiver fibrosisBiopsyHepacivirusImpulse (physics)behavioral disciplines and activitiesCohort StudiesElasticity Imaging TechniquesBiopsyotorhinolaryngologic diseasesMedicineHumansProspective StudiesAcoustic radiation forceAgedHepatologybiologymedicine.diagnostic_testbusiness.industryarfi fibroscan hcv fibrosisGastroenterologyReproducibility of ResultsHepatitis CHepatitis C ChronicMiddle Agedbiology.organism_classificationmedicine.diseaseROC CurveElasticity Imaging TechniquesRNA ViralFemalesense organsRadiologyTransient elastographybusinesspsychological phenomena and processes
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Current practice of hepatitis C treatment in Southern Italy.

2010

Abstract Background Only a small proportion of subjects referring to hospitals for hepatitis C virus (HCV) positivity receives antiviral therapy. Aim To evaluate the rate of antiviral treatment and the causes for no treatment in HCV-RNA positive subjects seen in hospital settings. Patients and methods A prospective study enrolling over a 6-month period (February–July 2009) all consecutive anti-HCV positive subjects initially referred (naive patients) to 12 liver units in Southern Italy for HCV treatment. Results Out of 608 subjects evaluated, 74 (12.2%) had no detectable HCV-RNA in the serum and thus were excluded. Of the remaining 534 HCV-RNA positive subjects, 357 (66.9%) were not treated…

AdultMalemedicine.medical_specialtyMultivariate analysisHepatitis C virusAlcohol abuseHepacivirusInterferon alpha-2medicine.disease_causeAntiviral AgentsPolyethylene GlycolsTreatment RefusalSex FactorsInternal medicineRibavirinHumansMedicineProspective StudiesProspective cohort studyAgedHepatologybusiness.industryGastroenterologyAntiviral therapyInterferon-alphaAlanine TransaminaseHepatitis CHepatitis C AntibodiesMiddle Agedmedicine.diseaseHepatitis CRecombinant ProteinsAlcoholismTreatment OutcomeItalyCurrent practiceImmunologyHCVHcv treatmentEducational StatusRNA ViralFemalebusiness
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Liver stiffness, a non-invasive marker of liver disease: a core study group report

2010

The ability to evaluate liver stiffness non-invasively in clinical practice by measuring transient elastography using FibroScan® has resulted in considerable interest and enthusiasm. A core study group, organized by the Italian Association for the Study of the Liver, has assessed the usefulness of FibroScan® in the diagnosis and management of liver disease in clinical practice. The group concluded that FibroScan® is a valuable, non-invasive technique and have developed a consensus report form for registering transient elastography results. In this article, we report the findings of the study group.

PharmacologyLiver Cirrhosismedicine.medical_specialtyCore (anatomy)business.industryNon invasiveHepatitis Bmedicine.diseaseHepatitis BGastroenterologyClinical Practiceliver stiffnessLiver diseaseInfectious DiseasesLiverLiver stiffnessInternal medicinemedicineElasticity Imaging TechniquesPharmacology (medical)Transient elastographybusinessLiver pathologyBiomarkers
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