0000000001008162

AUTHOR

Wolfgang A. Bethge

showing 1 related works from this author

Prognostic Factors Affecting Outcome after Allogeneic Transplantation for Hematological Malignancies from Unrelated Donors: Results from a Randomized…

2012

Several prognostic factors for the outcome after allogeneic hematopoietic stem-cell transplant (HSCT) from matched unrelated donors have been postulated from registry data; however, data from randomized trials are lacking. We present analyses on the effects of patient-related, donor-related, and treatment-related prognostic factors on acute GVHD (aGVHD), chronic GVHD (cGVHD), relapse, nonrelapse mortality (NRM), disease-free survival (DFS), and overall survival (OS) in a randomized, multicenter, open-label, phase III trial comparing standard graft-versus-host-disease (GVHD) prophylaxis with and without pretransplantation ATG-Fresenius (ATG-F) in 201 adult patients receiving myeloablative co…

MaleOncologyTransplantation Conditioningmedicine.medical_treatmentMedizinGraft vs Host DiseaseHematopoietic stem cell transplantationSeverity of Illness Indexlaw.invention0302 clinical medicineRandomized controlled trialHLA Antigenslawimmune system diseaseshemic and lymphatic diseasesAllogeneic hematopoietic stem-cell transplantationMedicineProspective StudiesProspective cohort studyHematologyHistocompatibility TestingAge FactorsHematopoietic Stem Cell TransplantationHematologyMiddle Aged3. Good healthSurvival Ratesurgical procedures operative030220 oncology & carcinogenesisAcute DiseaseFemaleUnrelated DonorsAdultmedicine.medical_specialtyAllogeneic transplantationAdolescentGraft-versus-host-disease prophylaxis03 medical and health sciencesInternal medicineHumansTransplantation HomologousHLA-matchingSurvival rateAntilymphocyte SerumTransplantationbusiness.industryMyeloablative AgonistsTransplantationChronic DiseaseImmunologyTransplantation Conditioningbusiness030215 immunologyBiology of Blood and Marrow Transplantation
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