Effect of 3rd-order aberrations on human vision

To investigate the effect of 3rd-order aberrations on human vision.Grupo de Ciencias de la Visión, University of Murcia, Murcia, Spain.The 3rd-order aberrations coma and trefoil were induced with purpose-designed soft contact lenses, 3 inducing coma (low [0.05 microm], medium [0.13 microm], high [1.03 microm]) and 3 inducing trefoil (low [0.07 microm], medium [0.17 microm], high [0.96 microm]). Monocular high-contrast (HCVA) and low-contrast (LCVA) visual acuities and contrast sensitivity were measured in 11 subjects wearing contact lenses with a 5.0 mm artificial pupil.The reduction in HCVA and LCVA was statistically significant only for the highest coma and trefoil values (P.0001). For co…