Author: Eva Kalkum

0000000001009366

AUTHOR

Eva Kalkum

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Meta-analysis of Randomized Controlled Trials and Individual Patient Data Comparing Minimally Invasive With Open Oesophagectomy for Cancer

2021

Minimally invasive oesophagectomy (MIO) for oesophageal cancer may reduce surgical complications compared with open oesophagectomy. MIO is, however, technically challenging and may impair optimal oncological resection. The aim of the present study was to assess if MIO for cancer is beneficial.A systematic literature search in MEDLINE, Web of Science and CENTRAL was performed and randomized controlled trials (RCTs) comparing MIO with open oesophagectomy were included in a meta-analysis. Survival was analysed using individual patient data. Random-effects model was used for pooled estimates of perioperative effects.Among 3219 articles, six RCTs were identified including 822 patients. Three-yea…

medicine.medical_specialtyEsophageal Neoplasmsmedicine.medical_treatment610 Medicine & healthLower risklaw.inventionRandomized controlled triallawOpen ResectionMedicineHumansMinimally Invasive Surgical ProceduresRandomized Controlled Trials as Topic10217 Clinic for Visceral and Transplantation Surgerybusiness.industryCancerOdds ratioPerioperativeLength of Staymedicine.diseaseSurgery2746 SurgeryEsophagectomyTreatment OutcomeEsophagectomyMeta-analysisSurgerybusiness

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