0000000001014978

AUTHOR

Peter Karl Jacobsen

showing 2 related works from this author

40(th) EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004

2004

0303 health sciencesmedicine.medical_specialtybusiness.industryEASDEndocrinology Diabetes and MetabolismHuman physiologymedicine.disease03 medical and health sciences0302 clinical medicineDiabetes mellitusFamily medicineInternal MedicineMedicinebusiness030217 neurology & neurosurgery030304 developmental biology
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Tubular markers are associated with decline in kidney function in proteinuric type 2 diabetic patients.

2011

Our aim was to investigate u-NGAL, u-KIM1 and p-FGF23 and prediction of decline in kidney function in type 2 diabetic patients with proteinuria.We performed a follow-up study, follow-up median (range) 3.5 (1-5) years. At baseline u-NGAL, u-KIM1 and p-FGF23 (ELISA) was measured and patients were followed yearly with estimated(e)-GFR (MDRD) and u-albumin.We included 177 patients (44 women), mean age (SD) 59 (9) years. eGFR 90 (24) ml/min/1.73 m(2) at baseline, u-albumin: median (interquartile range) 104 (39-238) mg/24 h. Patients with levels of u-KIM1 in the highest quartile had a greater decline in eGFR than patients with the lowest quartile 6.0 (5.4) versus 3.2 (5.5) ml/min/1.73 m(2) per ye…

Blood GlucoseMalemedicine.medical_specialtyEndocrinology Diabetes and MetabolismUrologyRenal functionEnzyme-Linked Immunosorbent AssayType 2 diabetesKidneyEnd stage renal diseaseDiabetic nephropathyEndocrinologyInterquartile rangeDiabetes mellitusInternal medicineInternal MedicinemedicineHumansDiabetic NephropathiesProteinuriabusiness.industryGeneral MedicineMiddle Agedmedicine.diseaseFibroblast Growth Factor-23ProteinuriaEndocrinologyKidney TubulesQuartileDiabetes Mellitus Type 2Disease ProgressionFemalemedicine.symptombusinessBiomarkersAcute-Phase ProteinsFollow-Up StudiesGlomerular Filtration RateDiabetes research and clinical practice
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