0000000001024375

AUTHOR

A. Vilella

showing 2 related works from this author

Influenza vaccine effectiveness in preventing outpatient, inpatient, and severe cases of laboratory-confirmed influenza.

2013

Background. In most seasons, the influenza vaccine is effective in preventing influenza, but it is not clear whether it is equally effective in preventing mild and severe cases. We designed a case-control study to compare the effectiveness of the influenza vaccine in preventing outpatient, inpatient, and severe or fatal cases of laboratory-confirmed influenza. Methods. Hospitalized patients (n = 691) with laboratory-confirmed influenza in the 2010–2011 season recruited in 29 Spanish hospitals were individually matched by age, admission/visit date, and province with an outpatient with laboratory-confirmed influenza and an outpatient control. Severe cases were considered those patients admitt…

Microbiology (medical)AdultMalemedicine.medical_specialtyAdolescentInfluenza vaccineLower riskLogistic regressionYoung AdultPregnancyInternal medicineIntensive careInfluenza HumanOutpatientsmedicineHumansIntensive care medicineChildAgedAged 80 and overCross InfectionInpatientsbusiness.industryConfoundingInfant Newbornvirus diseasesInfantOdds ratioMiddle AgedPrognosisConfidence intervalVaccinationCommunity-Acquired InfectionsHospitalizationInfectious DiseasesInfluenza VaccinesSpainCase-Control StudiesChild PreschoolFemalebusinessClinical infectious diseases : an official publication of the Infectious Diseases Society of America
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Effect of antiviral treatment in older patients hospitalized with confirmed influenza

2019

Abstract Seasonal influenza causes significant morbidity and mortality in people aged ≥65 years. Antiviral treatment can reduce complications and disease severity. The objective of this study was to investigate the effect of antiviral treatment in patients aged ≥65 years hospitalized with confirmed influenza in preventing intensive care unit (ICU) admission or death. A retrospective cohort study was carried out in 20 hospitals from seven Spanish regions during 2013–2015 in patients aged ≥65 years. Hospitalized cases of laboratory-confirmed influenza were selected. To assess the association between antiviral treatment and ICU admission or death, the adjusted odds ratios (aOR) and their 95% c…

Male0301 basic medicinemedicine.medical_specialtyHospitalized patients030106 microbiologyLogistic regressionAntiviral AgentsTime-to-Treatmentlaw.invention03 medical and health sciencesOseltamivirOlder patientsAdrenal Cortex HormoneslawVirologyInternal medicineInfluenza HumanHumansMedicineAntiviral treatmentAgedRetrospective StudiesPharmacologybusiness.industryRetrospective cohort studyOdds ratioIntensive care unitConfidence intervalHospitalizationIntensive Care UnitsTreatment Outcome030104 developmental biologyFemalebusinessAntiviral Research
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