0000000001025619

AUTHOR

M Valentini

showing 6 related works from this author

Addition of either pioglitazone or a sulfonylurea in type 2 diabetic patients inadequately controlled with metformin alone: impact on cardiovascular …

2012

Abstract Background and aims Metformin is the first-line therapy in type 2 diabetes. In patients inadequately controlled with metformin, the addition of a sulfonylurea or pioglitazone are equally plausible options to improve glycemic control. However, these drugs have profound differences in their mechanism of action, side effects, and impact on cardiovascular risk factors. A formal comparison of these two therapies in terms of cardiovascular morbidity and mortality is lacking. The TOSCA.IT study was designed to explore the effects of adding pioglitazone or a sulfonylurea on cardiovascular events in type 2 diabetic patients inadequately controlled with metformin. Methods Multicentre, random…

Blood GlucoseMaleBIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICAEndocrinology Diabetes and Metabolismpioglitazone sulfonylurea type 2 diabetes metformin cardiovascular eventsMedicine (miscellaneous)Type 2 diabetesSettore MED/13 - EndocrinologiaBody Mass Indexlaw.inventionRandomized controlled trialRisk FactorslawSurveys and QuestionnairesCardiovascular DiseasepioglitazonepiogllitazoneStrokeDiabetes Therapy PioglitazoneNutrition and DieteticsDiabetesThiazolidinedionecardiovascular events; pioglitazone; Type 2 Diabetes Mellitus; sulphonylureasType 2 diabetesMiddle AgedMetforminSulfonylurea CompoundTreatment OutcomeTolerabilitysulphonylureasCardiovascular DiseasesDrug Therapy CombinationFemaletype 2 diabetesCardiology and Cardiovascular MedicineHumanmedicine.drugmedicine.medical_specialtyEndpoint Determinationsulfonylureacardiovascualr eventSudden deathFollow-Up Studiecardiovascular eventsInternal medicineDiabetes mellitusmedicineHumansHypoglycemic Agentssulfonylureasinterventio trialtype 2 diabetes; cardiovascular events; pioglitazone; sulfonylureas; randomized controlled trialAgedHypoglycemic AgentQuestionnairebusiness.industryRisk Factormedicine.diseaseSurgeryType 2 Diabetes MellitusSulfonylurea CompoundsDiabetes Mellitus Type 2randomized controlled trialQuality of LifeThiazolidinedionesTherapybusinessmetforminPioglitazoneFollow-Up Studies
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ERROR AND UNCERTAINTY ANALYSIS OF RESIDUAL STRESS EVALUATION BY USINGTHE RING-CORE METHOD

2014

The Ring-Core Method is a technique used for the experimental analysis of the residual stresses in mechanical components. For uniform and non-uniform residual stresses estimation, the use of the method leads in general to accurate results but, unfortunately at present the user does not have appropriate procedures to correct the obtained results from systematic errors as well as to estimate the uncertainty due to random errors. In order to overcome such drawbacks, in the present work, the procedures for the correction of the effects of the main error sources and for the stress uncertainty estimation, are proposed. The practical application of such procedures allow the user to highlight the r…

Settore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineRing-core method residual stresses uncertainty estimation.
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Pristionchus sp. (Rhabditida: Diplogastridae) from Italian populations of Anoplophora chinensis Forster (Coleoptera: Cerambycidae).

2009

Priostonchus sp. n. (Rhabditida: Diplogastridae) is described from a population of Citrus Longhorn Beetles. Alive adults of this Cerambycid were collected from Acer saccharinum trees at Assago and Parabiago (Villastanza), two localities near Milan (Italy). The natural occurrence of the entomogenous nematode in the beetle was not frequent and widespread in the study area. Preliminary laboratory infectivity tests highlight the potential parasitic nature of the nematode. However, it was not successfully maintained in storage and culture. The diplogasterid Pristionchus sp. has rather complicate systematic thus a biomolecular analysis based on DNA is necessary for more specific identification an…

Settore AGR/11 - Entomologia Generale E ApplicataAnoplophora Entomopathogenic nematodes EPN Longhorn beetles
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Search for eccentric binary black hole mergers with advanced LIGO and advanced Virgo during their first and second observing runs

2019

When formed through dynamical interactions, stellar-mass binary black holes may retain eccentric orbits ($e>0.1$ at 10 Hz) detectable by ground-based gravitational-wave detectors. Eccentricity can therefore be used to differentiate dynamically-formed binaries from isolated binary black hole mergers. Current template-based gravitational-wave searches do not use waveform models associated to eccentric orbits, rendering the search less efficient to eccentric binary systems. Here we present results of a search for binary black hole mergers that inspiral in eccentric orbits using data from the first and second observing runs (O1 and O2) of Advanced LIGO and Advanced Virgo. The search uses min…

AstrofísicaGravitació010504 meteorology & atmospheric sciencesIMPACTAstronomyWAVESBinary numberAstrophysicsgravitational waves; black hole; LIGO; VirgoLIGO-Virgo01 natural sciencesRendering (computer graphics)GravitationElliptical orbitCOMPACT-OBJECT BINARIESblack holeEccentricCOMPACT-OBJECT BINARIES; YOUNG STAR-CLUSTERS; EVOLUTION; PERTURBATIONS; PROGENITORS; IMPACT;WAVESEccentricity (behavior)LIGO010303 astronomy & astrophysicsorbitQCmedia_commonQBSettore FIS/01PhysicsHigh Energy Astrophysical Phenomena (astro-ph.HE)PROGENITORSAstrophysical black holesGravitational waves; Elliptical orbits; Astrophysical black holesPERTURBATIONSJustice and Strong Institutionsgravitational wavesPhysical SciencesAstrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical PhenomenaYOUNG STAR-CLUSTERSGravitational wavedata analysis methodSDG 16 - Peacemedia_common.quotation_subjectGravitational waves Elliptical orbits Astrophysical black holesFOS: Physical sciencesAstrophysics::Cosmology and Extragalactic AstrophysicsAstronomy & AstrophysicsGravitational wavesElliptical orbitsGeneral Relativity and Quantum CosmologySettore FIS/05 - Astronomia e AstrofisicaBinary black holebinary: coalescencestatistical analysis0103 physical sciencesWaveformSTFC0105 earth and related environmental sciencesScience & Technologybinary: formationVirgoSDG 16 - Peace Justice and Strong Institutionsgravitational radiationRCUKAstronomy and Astrophysics/dk/atira/pure/sustainabledevelopmentgoals/peace_justice_and_strong_institutionsLIGOEVOLUTIONgravitational radiation detectordetector: sensitivityVIRGOPhysics and Astronomyblack hole: binarySpace and Planetary Sciencegravitational radiation: emissioneccentric BBHstar: mass[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
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Search for Subsolar Mass Ultracompact Binaries in Advanced LIGO's Second Observing Run

2019

We present a search for subsolar mass ultracompact objects in data obtained during Advanced LIGO’s second observing run. In contrast to a previous search of Advanced LIGO data from the first observing run, this search includes the effects of component spin on the gravitational waveform. We identify no viable gravitational-wave candidates consistent with subsolar mass ultracompact binaries with at least one component between \ud0.2\ud \ud \udM\ud⊙\ud–\ud1.0\ud \ud \udM\ud⊙\ud. We use the null result to constrain the binary merger rate of (\ud0.2\ud \ud \udM\ud⊙\ud, \ud0.2\ud \ud \udM\ud⊙\ud) binaries to be less than \ud3.7\ud×\ud10\ud5\ud \ud \udGpc\ud−\ud3\ud \udyr\ud−\ud1\udand the binary …

Dewey Decimal Classification::500 | Naturwissenschaften::550 | Geowissenschaftenbinary: massAstrofísicaGravitacióFormation modeldensity: fluctuationAstronomyGeneral Physics and Astronomydetector: networkspin01 natural sciencesGeneral Relativity and Quantum CosmologyLIMITSblack hole: formationddc:550black holeDark MatterAstrophysics::Solar and Stellar AstrophysicsLIGOQCQBnucleus: interactionSettore FIS/01astro-ph.HEHigh Energy Astrophysical Phenomena (astro-ph.HE)gravitational wave; physics; astronomyPhysicsarticleDensity fluctuationgravitational wavesPhysical Sciences[PHYS.GRQC]Physics [physics]/General Relativity and Quantum Cosmology [gr-qc]astro-ph.COAstrophysics::Earth and Planetary AstrophysicsAstrophysics - High Energy Astrophysical Phenomenablack hole: primordialGravitationAstrophysics - Cosmology and Nongalactic AstrophysicsMatter densitydensity: primordialCosmology and Nongalactic Astrophysics (astro-ph.CO)coolinggr-qcAstrophysics::High Energy Astrophysical PhenomenaPhysics MultidisciplinaryCooling mechanismPrimordial black holesFOS: Physical sciencesdark matter: densityGeneral Relativity and Quantum Cosmology (gr-qc)Astrophysics::Cosmology and Extragalactic AstrophysicsGravity wavesNuclear interactionGravitation and AstrophysicsMergingGeneral Relativity and Quantum Cosmologynull resultSettore FIS/05 - Astronomia e Astrofisicabinary: coalescence0103 physical sciencesddc:530010306 general physicsAstrophysics::Galaxy AstrophysicsSTFCScience & Technologymass: solarCosmologiaStellar evolutions010308 nuclear & particles physicsMatter fractionsgravitational radiationRCUKblack hole: massGalaxiesbinary: compactStarsgravitational radiation detectordetector: sensitivityVIRGOPhysics and Astronomygravitational radiation: emissionDewey Decimal Classification::500 | Naturwissenschaften::530 | Physik[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]Gravitational waves Black holes (astronomy) Gravitational self forcePhysical Review Letters
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Increasing the Astrophysical Reach of the Advanced Virgo Detector via the Application of Squeezed Vacuum States of Light

2019

Current interferometric gravitational-wave detectors are limited by quantum noise over a wide range of their measurement bandwidth. One method to overcome the quantum limit is the injection of squeezed vacuum states of light into the interferometer's dark port. Here, we report on the successful application of this quantum technology to improve the shot noise limited sensitivity of the Advanced Virgo gravitational-wave detector. A sensitivity enhancement of up to 3.2±0.1 dB beyond the shot noise limit is achieved. This nonclassical improvement corresponds to a 5%-8% increase of the binary neutron star horizon. The squeezing injection was fully automated and over the first 5 months of the thi…

neutron star: binaryGravitational waves detectionGeneral Physics and Astronomy01 natural sciencesvacuum stateNOISEinterferometric detectorLIGOnoise: quantumgravitational waves; squeezing; vacuumSettore FIS/01PhysicsQuantum opticsPhysicsQuantum limitQuantum noiseDetectorPhysical Sciencesgravitational waves squeezed lightinterferometric detectorsGravitational waveSqueezed coherent statePhysics Multidisciplinarysqueezed stateGravitation and AstrophysicshorizonGravitational wavesGeneral Relativity and Quantum CosmologyOpticsSettore FIS/05 - Astronomia e Astrofisica0103 physical sciences[PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det]SDG 7 - Affordable and Clean Energy010306 general physicsenhancementAstrophysiqueScience & Technology/dk/atira/pure/sustainabledevelopmentgoals/affordable_and_clean_energybusiness.industryShot noisegravitational radiationgravitational waves thermal noisesensitivityLIGOdetector: sensitivityQuantum technology* Automatic Keywords *VIRGOinjectionPhysics and Astronomygravitational radiation detector: interferometerGravitational waves; interferometric detectors; noiseWAVEbusiness[PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]gravitational waves nonlinear optics quantum opticsPhysical Review Letters
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