0000000001026591

AUTHOR

Raquel Núñez

showing 7 related works from this author

Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients.

2018

Background Heart failure (HF) is associated with a high rate of readmissions within 30 days post-discharge and in the following year, especially in frail elderly patients. Biomarker data are scarce in this high-risk population. This study assessed the value of early post-discharge circulating levels of ST2, NT-proBNP, CA125, and hs-TnI for predicting 30-day and 1-year outcomes in comorbid frail elderly patients with HF with mainly preserved ejection fraction (HFpEF). Methods Blood samples were obtained at the first visit shortly after discharge (4.9 ± 2 days). The primary endpoint was the composite of all-cause mortality or HF-related rehospitalization at 30 days and at 1 year. All-cause mo…

Malemedicine.medical_specialtyFrail ElderlyPopulationComorbidity030204 cardiovascular system & hematologylcsh:GeriatricsPatient Readmission03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineCause of DeathNatriuretic Peptide BrainClinical endpointmedicineHumans030212 general & internal medicineProspective StudieseducationProspective cohort studyAgedAged 80 and overHeart Failureeducation.field_of_studyPredictive markerSurrogate endpointbusiness.industryHazard ratioMembrane Proteinsmedicine.diseasePrognosisComorbidityPeptide Fragmentslcsh:RC952-954.6CA-125 AntigenBiomarker (medicine)FemaleGeriatrics and GerontologybusinessBiomarkersResearch ArticleFollow-Up Studies
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Additional file 3: of Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

2018

Table S3. Cox regression analyses for 1-year HF-related hospitalization. A competing risk strategy using the Gray method was adopted, considering death as the competing risk in both univariate and multivariate Cox regression analyses. (DOCX 27 kb)

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Additional file 2: of Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

2018

Table S2. Cox regression analyses for 30-day rehospitalization. A competing risk strategy using the Gray method was adopted, considering death as the competing risk in both univariate and multivariate Cox regression analyses. (DOCX 27 kb)

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Additional file 3: of Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

2018

Table S3. Cox regression analyses for 1-year HF-related hospitalization. A competing risk strategy using the Gray method was adopted, considering death as the competing risk in both univariate and multivariate Cox regression analyses. (DOCX 27 kb)

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Additional file 2: of Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

2018

Table S2. Cox regression analyses for 30-day rehospitalization. A competing risk strategy using the Gray method was adopted, considering death as the competing risk in both univariate and multivariate Cox regression analyses. (DOCX 27 kb)

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Additional file 1: of Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

2018

Table S1. Correlations between studied biomarkers. Correlation between the different studied biomarkers was performed using Pearson correlation test of log-transformed values of each biomarker. (DOCX 25 kb)

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Additional file 1: of Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients

2018

Table S1. Correlations between studied biomarkers. Correlation between the different studied biomarkers was performed using Pearson correlation test of log-transformed values of each biomarker. (DOCX 25 kb)

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