0000000001030244

AUTHOR

Castaman Giancarlo

showing 1 related works from this author

Cancers in Patients with von Willebrand Disease: A Survey from the Italian Association of Haemophilia Centres

2015

Besides its essential role in hemostasis, there is growing evidence that von Willebrand factor (VWF) has an additional antitumor effect. To elucidate the clinical significance of this biological activity we conducted a retrospective study on cancers among Italian patients with von Willebrand disease (VWD) on behalf of the Italian Association of Haemophilia Centres (AICE). A questionnaire to collect demographic, clinical, and treatment data of VWD patients with cancer was sent to all the 54 Italian Haemophilia Treatment Centres (HTCs) members of AICE. Overall, 18 HTCs (33%) provided information on 92 VWD patients (61 alive and 31 deceased) with 106 cancers collected during the period 1981 to…

Adultcongenital hereditary and neonatal diseases and abnormalitiesPediatricsmedicine.medical_specialtySettore MED/09 - Medicina InternaPopulationbleeding; cancer; mortality; von Willebrand disease; Hematology; Cardiology and Cardiovascular MedicineHaemophiliaHospitals Specialbleeding; cancer; mortality; von Willebrand disease; Adult; Aged; Aged 80 and over; Humans; Italy; Middle Aged; Prospective Studies; Hospitals Special; Neoplasms; Surveys and Questionnaires; von Willebrand Diseases; Hematology; Cardiology and Cardiovascular MedicineVon Willebrand factorNeoplasmsSurveys and Questionnaireshemic and lymphatic diseases80 and overmedicineVon Willebrand diseaseHumanscancerProspective StudiesDesmopressinProspective cohort studyeducationAgedAged 80 and overeducation.field_of_studySpecialbiologybusiness.industryRetrospective cohort studyHematologyMiddle Agedmedicine.diseasebleedingmortalityHospitalsbleeding; cancer; mortality; von Willebrand disease; Adult; Aged; Aged 80 and over; Humans; Italy; Middle Aged; Prospective Studies; Hospitals Special; Neoplasms; Surveys and Questionnaires; von Willebrand Diseasesvon Willebrand DiseasesItalyHemostasisbiology.proteinbusinessvon Willebrand diseaseCardiology and Cardiovascular Medicinemedicine.drug
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