0000000001030307

AUTHOR

Raj K. Gupta

showing 1 related works from this author

Cellular ionic alterations with age: relation to hypertension and diabetes.

2000

BACKGROUND: Cytosolic free calcium (Cai) and magnesium (Mgi) are vital to cellular homeostasis and function. OBJECTIVE: To evaluate cellular divalent cations in normal subjects at different ages and their relationship to ion levels in essential hypertension and diabetes. DESIGN: A cross-sectional study. SETTING: A university hospital in New York. PARTICIPANTS: A total of 103 subjects (32 older, 71.1 ± 1.2 y/o, and 71 young/middle aged subjects, 51.1 ± 2.3 y/o). INTERVENTION: Oral glucose tolerance test. MEASUREMENTS: 19F and 31P NMR spectroscopy were used to measure Cai and Mgi levels in erythrocytes from normal (>65 y/o, n = 11; 65 y/o, n = 9; 65 y/o, n = 12; <65 y/o, n = 15) subjects; the…

Blood GlucoseMalemedicine.medical_specialtyAgingErythrocytesMagnetic Resonance Spectroscopymedicine.medical_treatmentCellular homeostasisEssential hypertensionCytosolInternal medicineDiabetes mellitusmedicineHumansInsulinMagnesiumMagnesium ionAgedAged 80 and overGlucose tolerance testmedicine.diagnostic_testbusiness.industryInsulinAge FactorsGlucose Tolerance TestMiddle Agedmedicine.diseaseCausalityEndocrinologyGlycemic indexBlood pressureCross-Sectional StudiesDiabetes Mellitus Type 2Case-Control StudiesHypertensionCalciumFemaleGeriatrics and GerontologybusinessJournal of the American Geriatrics Society
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