0000000001031694

AUTHOR

Francesca Bonura

showing 38 related works from this author

Left bundle branch block and myocardial infarction, a diagnosis not always easy: Our experience and review of literature

2012

The occurrence of left bundle branch block (LBBB) is quite common in clinical practice. The changes in cardiac repolarization, caused by this disorder of electric conduction, may mask the presence of an acute myocardial infarction (AMI), delaying the diagnostic-therapeutic iter, with an important impact on prognosis. We describe the case of a woman of 59 years with LBBB, came to our observation for a constrictive chest pain associated with dyspnea. The diagnostic workup for suspected acute coronary syndrome (ACS), initially conducted only on the analysis of the electrocardiogram (negative TnI at entry), showed the presence of coronary arteries free of stenosis. However, the diagnostic confi…

Left Bundle Branch Block (LBBB)medicine.medical_specialtyAcute coronary syndromebusiness.industryLeft bundle branch blockMyocardial InfarctionElectrocardiography in myocardial infarctionmedicine.diseaseChest painElectrocardiogramCoronary arteriesStenosismedicine.anatomical_structureInternal medicinemedicineCardiologyIn patientcardiovascular diseasesMyocardial infarctionmedicine.symptombusinessWorld Journal of Cardiovascular Diseases
researchProduct

C-REACTIVE PROTEIN AND FIBRINOGEN TO EVALUATE THE REAL RISK OF CEREBRO AND CARDIOVASCULAR EVENTS IN PATIENTS WITH DIEBETES MELLITUS

2004

C-REACTIVE PROTEIN FIBRINOGEN
researchProduct

Behavior of patients at high risk of developing contrast induced nephropathy after coronary procedures

2012

Contrast induced nephropathy atherosclerosis percutaneous coronary intervention coronary angiography
researchProduct

ATHEROSCLEROSIS AND MARKERS OF INFLAMMATION IN PATIENTS WITH METABOLIC SYNDROME

2005

medicine.medical_specialtybiologybusiness.industryC-reactive proteinInflammationFibrinogenmedicine.diseaseTunica intimamedicine.anatomical_structureInternal medicineImmunologyInternal Medicinemedicinebiology.proteinCardiologyIn patientMyocardial infarctionmedicine.symptomMetabolic syndromebusinessNational Cholesterol Education Programmedicine.drug
researchProduct

RUOLO DELL’ECOCOLOR DOPPLER TISSUTALE NELLA VALUTAZIONE DELLA CARDIOTOSSICITÀ DA CHEMIOTERAPICI

2010

Settore MED/06 - Oncologia MedicaSettore BIO/14 - FarmacologiaECOCOLOR DOPPLER TISSUTALE CARDIOTOSSICITÀ CHEMIOTERAPICISettore MED/11 - Malattie Dell'Apparato Cardiovascolare
researchProduct

INFLUENCE OF CAROTID AND PERIPHERAL ATHEROSCLEROSIS ON THE OUTCOME OF PATIENTS WITH ACUTE CORONARY SYNDROME

2006

CAROTID AND PERIPHERAL ATHEROSCLEROSIS ACUTE CORONARY SYNDROME
researchProduct

Markers of Inflammation and Infection Influence the Outcome of Patients With Baseline Asymptomatic Carotid Lesions

2005

Background and Purpose— It is still in debate whether the evaluation of markers of infection and inflammation may be of importance for cerebrovascular and cardiovascular prevention, and we aimed to investigate this field in a prospective 5-year clinical follow-up study in patients with early stages of atherosclerosis. Methods— We studied 668 subjects divided in 3 groups according to the results of carotid ultrasound examination: (1) normal subjects, if intima-media thickness (IMT) was <0.9 mm; (2) with IMT, if IMT was between 0.9 and 1.5 mm; and (3) with asymptomatic carotid plaque, if IMT was >1.5 mm. Traditional cardiovascular risk factors were investigated, and laboratory analysis…

Carotid Artery DiseasesMalePathologyTime FactorsCytomegalovirusFibrinogenCardiovascular SystematherosclerosiRisk FactorsStrokeUltrasonographyChlamydiabiologyChlamydophila pneumoniaeMiddle AgedLipidsEchocardiography DopplerStrokeC-Reactive ProteinCarotid ArteriesCardiovascular DiseasesDisease ProgressionFemalemedicine.symptomTunica MediaCardiology and Cardiovascular Medicinemedicine.drugmedicine.medical_specialtyCongenital cytomegalovirus infectionInfectionsAsymptomaticCentral nervous system diseaseSex FactorsInternal medicinemedicineHumanscarotid arterieAgedAdvanced and Specialized NursingAnalysis of VarianceHelicobacter pyloriVascular diseasebusiness.industryFibrinogenHelicobacter pyloriAtherosclerosisbiology.organism_classificationmedicine.diseaseinfectioninflammationImmunoglobulin GNeurology (clinical)Tunica IntimabusinessFollow-Up StudiesStroke
researchProduct

IL PROCESSO INFIAMMATORIO E LA FIBRILLAZIONE ATRIALE: RELAZIONE FRA I LIVELLI EMATICI DI PCR, FIBRINOGENO C E MMP-9 E DIFFERENTI PATTERN CLINICI DELL…

2011

Fibrillazzione atrialeMMP-9 Fibrinogeno PCR
researchProduct

L’ATEROSCLEROSI PERIFERICA COME MARKER DI MALATTIA CORONARICA

2007

aterosclerosi periferica malattia coronarica
researchProduct

COMPORTAMENTO DEI PAZIENTI AD ALTO RISCHIO DI SVILUPPARE NEFROPATIA INDOTTA DA MEZZO DI CONTRASTO DOPO CORONAROGRAFIA/ANGIOPLASTICA PERCUTANEA

2010

nefropatia mezzo di contrasto coronarografia
researchProduct

Timely recognition of cardiovascular toxicity by anticancer agents: a common objective of the pharmacologist, oncologist and cardiologist.

2011

Both conventional and new anticancer drugs can frequently cause adverse cardiovascular effects, which can span from subclinical abnormalities to serious life-threatening and sometimes fatal events. This review examines the principal basic and clinical elements that may be of profit to identify, prevent and treat such toxicities. Clearly, the accomplishment of such objectives requires the strong commitment and cooperation of different professional figures including, but not limited to, pharmacologists, oncologists and cardiologists. The aspect of anticancer drug cardiotoxicity seems to be somehow underestimated, mainly due to inadequate reporting of adverse reactions from oncology drugs in t…

Cardiovascular toxicityTime FactorsSettore MED/06 - Oncologia MedicaPharmacology toxicologyCardiologyAntineoplastic AgentsPharmacologyToxicologyMedical OncologyCardiotoxinsCardiovascular SystemProfessional RolePharmacovigilanceMedicineAnimalsHumansPhysician's RoleMolecular BiologyPharmacologyCardiotoxicitybusiness.industryCardiovascular toxicity Anthracyclines Tyrosine kinase inhibitors TrastuzumabSettore MED/11 - Malattie Dell'Apparato CardiovascolareAnticancer drugLaboratory PersonnelCardiovascular DiseasesSettore BIO/14 - FarmacologiaCardiology and Cardiovascular MedicinebusinessOncology drugsCardiovascular toxicology
researchProduct

ATHEROGENETIC MECHANISM AND MORPHOLOGIC CHARACTERISTIC OF ATHEROSCLEROTIC LESIONS IN DIFFERENT LOCATIONS-ARE THEY IDENTICAL?

2005

atherosclerosis
researchProduct

MARKERS OF INFLAMMATION AND RISK OF VASCULAR EVENTS IN PATIENTS WITH NON-INSULIN DEPENDANT DIABETES

2006

MARKERS OF INFLAMMATION CARDIOVASCULAR RISK
researchProduct

L’IPERTENSIONE ARTERIOSA E ALTRI FATTORI DI RISCHIO TRADIZIONALI ED EMERGENTI INFLUENZANO LA FUNZIONE ENDOTELIALE.

2004

IPERTENSIONE ARTERIOSA FUNZIONE ENDOTELIALE.
researchProduct

ROLE AND CLINICAL RELEVANCE OF NEW RISK FACTORS OF ATS

2005

RISK FACTORS OF ATHEROSLCEROSIS
researchProduct

DIABETE

2007

diabete
researchProduct

RUOLO DELLA SINDROME METABOLICA NELLA FIBRILLAZIONE ATRIALE

2010

fibrillazione atriale sindrome metabolica
researchProduct

FIBRILLAZIONE ATRIALE E DETERIORAMENTO COGNITIVO CEREBRALE

2010

fibrillazione atriale
researchProduct

RUOLO DELLA SINDROME METABOLICA NELLE SINDROMI CORONARICHE ACUTE

2010

sindrome metabolica sindromi coronariche
researchProduct

CORONARY AND PERIPHERAL ATHEROSCLEROSIS AND MARKERS OF INFLAMMATION IN PATIENTS WITH METABOLIC SYNDROME.

2005

CORONARY AND PERIPHERAL ATHEROSCLEROSIS MARKERS OF INFLAMMATION METABOLIC SYNDROME.
researchProduct

NUOVI FATTORI DI RISCHIO CARDIOVASCOLARE E ALIMENTAZIONE

2004

FATTORI DI RISCHIO CARDIOVASCOLARE ALIMENTAZIONE
researchProduct

Chemotherapy-induced cardiotoxicity: role of the tissue Doppler in the early diagnosis of left ventricular dysfunction.

2011

Cardiotoxicity is a common complication of chemotherapy. The aim of this study was to assess the cardiotoxicity of anticancer drugs using tissue Doppler imaging. A prospective study was carried out using patients with early breast cancer (72 women, median age: 57 ± 12 year) and other inclusion and exclusion criteria. Inclusion criteria were treatment with epirubicin, trastuzumab, fluorouracil, cyclophosphamide, taxotere, and taxolo; left ventricular ejection fraction (LVEF) of more than 50%; and absence of important pathologies. Exclusion criteria were presence of known heart disease, earlier exposure to mediastinal irradiation, and earlier chemotherapy. On the basis of treatment, patients …

Cardiac monitoring cardiotoxicity chemotherapy heart failure left ventricular dysfunction tissue Doppler imaging
researchProduct

Cardiotossicità da chemioterapici: considerazioni farmacologiche e ruolo dell’ecocardiografia nella sua valutazione clinica

2012

ecocardiografiaChemioterapiaSettore BIO/14 - Farmacologia
researchProduct

VALORE PROGNOSTICO E DECISIONALE DEL VO2 DI PICCO PER L'INDICAZIONE AL TRAPIANTO DI CUORE IN PAZIENTI CON SCOMPENSO CARDIACO CRONICO E TERAPIA BETABL…

2008

VO2 DI PICCO TRAPIANTO DI CUORE SCOMPENSO CARDIACO CRONICO
researchProduct

ASSOCIATION OF ELEVATED FIBRINOGEN AND C-REACTIVE PROTEIN LEVELS WITH CAROTID LESIONS IN PATIENTS WITH EARLY ONSET OF HYPERTENSION OR TYPE II DIABETE…

2006

FIBRINOGEN C-REACTIVE PROTEINCAROTID LESIONS
researchProduct

SINDROME METABOLICA ED ATEROSCLEROSI PRECLINICA CAROTIDEA IN UNA POPOLAZIONE GIOVANE CON ALTERATO STILE DI VITA

2010

sindrome metabolica aterosclerosi
researchProduct

LINEE GUIDA NEL DOLORE TORACICO ACUTO.

2004

DOLORE TORACICO ACUTO.
researchProduct

RELAZIONE FRA I LIVELLI EMATICI DI PCR, FIBRINOGENO C E MMP-9 E DIFFERENTI PATTERN CLINICI DELL'ARITMIA

2010

fibrinogeno pcr aritmia
researchProduct

ELEVATED C-REATIVE PROTEIN LEVELS ARE STRONG PREDICTOR OF CLINICAL EVENTS IN HYPERTENSIVE PATIENTS WITH EARLY STAGES OF ATHEROSCLEROSIS

2006

C-REATIVE PROTEIN ATHEROSCLEROSIS
researchProduct

LA PROTEINA C REATTIVA ED IL FIBRINOGENO NELLA VALUTAZIONE DEL RISCHIO REALE DI EVENTI VASCOLARI IN PAZIENTI CON DIABETE MELLITO TIPO II.

2004

PROTEINA C REATTIVA FIBRINOGENO DIABETE MELLITO TIPO II.
researchProduct

INFLUENZA PROGNOSTICA DELL’ATEROSCLEROSI CAROTIDEA O PERIFERICA IN PAZIENTI CON SINDROMI CORONARICHE ACUTE.

2006

ATEROSCLEROSI CAROTIDEA SINDROMI CORONARICHE ACUTE.
researchProduct

DIAGNOSTIC APPROACH TO THE PATIENTS WITH SUSPICION OF MULTIFOCAL DISEASE

2005

MULTIFOCAL DISEASE
researchProduct

[Cardiovascular risk profile of patients with psoriasis].

2013

The aim of this study was to assess the cardiovascular risk profile of patients with psoriasis compared to patients without psoriasis. A case-control assay was performed using 143 cases (psoriasis patients) and 104 controls (patients without psoriasis). We assessed the presence of hypertension, lipid profile (HDL, triglycerides), diabetes, and body mass index in both cases and controls. Psoriasis patients showed an unfavorable cardiovascular risk profile and a higher risk of cardiovascular events and metabolic syndrome than patients without psoriasis.

Cardiovascular risk psoriasis
researchProduct

Risk factors for contrast induced nephropathy: A study among Italian patients

2012

This study aimed to make a profile of patients at highest risk of developing contrast induced nephropathy (CIN) in order to take appropriate prevention measures. 591 patients undergoing coronary procedures were divided into two groups: patients with (CIN-group) and without (no-CIN) an increase in creatinine level equal or more than 25% from baseline values within 24-48 h after the coronary procedure. All patients underwent an accurate anamnesis, objective exam, hematochemical measurements, and diagnostic exams. The results of this study while confirming that, average age (p = 0.01), diabetes mellitus (p < 0.0001), base line renal insufficiency (p = 0.0001), diuretic therapy (p = 0.002), hig…

Malemedicine.medical_specialtylcsh:Diseases of the circulatory (Cardiovascular) systemTime Factorsmedicine.medical_treatmentCoronary angiographyContrast-induced nephropathylcsh:SurgeryContrast MediaRisk AssessmentGastroenterologyNephropathyPercutaneous coronary interventionchemistry.chemical_compoundContrast induced nephropathyRisk FactorsDiabetes mellitusInternal medicineOdds RatiomedicineHumansContrast nephropathyAgedSubclinical infectionCreatinineChi-Square Distributionbusiness.industryPercutaneous coronary interventionOdds ratiolcsh:RD1-811Middle Agedmedicine.diseaseAtherosclerosisUp-RegulationSurgeryLogistic ModelsItalychemistrylcsh:RC666-701CreatinineMultivariate AnalysisFemaleKidney DiseasesOriginal ArticleCardiology and Cardiovascular MedicinebusinessChi-squared distributionBiomarkersIndian Heart Journal
researchProduct

The treatment of venous leg ulcers: a new therapeutic use of iloprost

2007

Background: We conducted a study using an intravenous (i.v.) infusion of iloprost in the treatment of venous ulcers to verify whether the association of i.v. iloprost + local therapy + elastic compression has a favorable effect when compared with traditional treatment with local therapy and elastic compression. Study Design: We evaluated the effects of iloprost in 98 consecutive patients with noncomplicated venous ulcers of lower limbs subdivided into 2 groups: the first group (48 patients) received iloprost in saline solution for 3 weeks and the second group (50 patients) received a venous infusion of a saline solution. The patients were examined at baseline time 0 (first visit) and then a…

Malemedicine.medical_specialtyElastic compressionmedicine.medical_treatmentIschemiaPlacebo groupDrug Administration Schedulelaw.inventionRandomized controlled triallawmedicineHumansSingle-Blind MethodIloprostInfusions IntravenousVeinSalineDose-Response Relationship Drugbusiness.industryvenous ulcersiloprostLeg UlcerSignificant differenceMiddle Agedmedicine.diseaseCombined Modality TherapySurgeryTreatment Outcomemedicine.anatomical_structureDebridementAnesthesiaAnti-Infective Agents LocalFemaleSurgeryVENOUS LEG ULCERS ILOPROSTbusinessPlatelet Aggregation InhibitorsStockings CompressionIloprostmedicine.drug
researchProduct

Significato clinico e prognostico dell'aterosclerosi carotidea nella valutazione del rischio cardiovascolare globale

2007

aterosclerosi carotidearischio cardiovascolare
researchProduct

Chemotherapy cardiotoxicity: cardioprotective drugs and early identification of cardiac dysfunction.

2016

Background: Chemotherapy cardiotoxicity is an emerging problem and it is very important to prevent cardiac dysfunction caused by anticancer drugs. The aim of this study was to assess the alterations of the cardiac function induced by chemotherapy in a follow-up of 2 years and to evaluate the cardioprotective role of angiotensin-converting enzyme inhibitors (ACEIs) in the prevention of cardiac dysfunction. Methods: A prospective study was carried out using patients with breast cancer (85 women; median age 57W12years) and other inclusion and exclusion criteria. On the basis of treatment, patients were divided into six groups: fluorouracil-epirubicincyclophosphamide, FEC (group A); FEC and tra…

Cardiac function curveAdultmedicine.medical_specialtyCardiotonic Agentsmedicine.medical_treatmentAngiotensin-Converting Enzyme InhibitorsBreast Neoplasms030204 cardiovascular system & hematologyBioinformaticsCardiac dysfunctionAngiotensin-converting enzyme inhibitor; Cardiotoxicity; Chemotherapy; Prevention; Tissue Doppler imaging; Adult; Aged; Aged 80 and over; Angiotensin-Converting Enzyme Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiotonic Agents; Cardiotoxicity; Early Diagnosis; Echocardiography Doppler; Female; Follow-Up Studies; Humans; Middle Aged; Prospective Studies03 medical and health sciencesTissue Doppler imaging0302 clinical medicinecardiac toxicity anti cancer drugs cardiac dysfunctionInternal medicineAntineoplastic Combined Chemotherapy Protocols80 and overMedicineChemotherapyHumansProspective StudiesAgedAged 80 and overCardiotoxicityChemotherapybusiness.industryPreventionFollow up studiesDopplerGeneral MedicineMiddle AgedCardiotoxicityEchocardiography DopplerClinical trialEarly DiagnosisAngiotensin-converting enzyme inhibitorEchocardiography030220 oncology & carcinogenesiscardiovascular systemCardiologyFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesJournal of cardiovascular medicine (Hagerstown, Md.)
researchProduct

DO MARKERS OF PRECLINICAL ATHEROSCLEROSIS INFLUENCE GLOBAL CARDIOVASCULAR RISK?

2007

DO MARKERS OF PRECLINICAL ATHEROSCLEROSIS INFLUENCE GLOBAL CARDIOVASCULAR RISK?

DO MARKERS OF PRECLINICAL ATHEROSCLEROSIS INFLUENCE GLOBAL CARDIOVASCULAR RISK?
researchProduct