0000000001034425

AUTHOR

Christoph Grunau

showing 2 related works from this author

Morphological and genomic characterisation of the Schistosoma hybrid infecting humans in Europe reveals admixture between Schistosoma haematobium and…

2021

Schistosomes cause schistosomiasis, the world’s second most important parasitic disease after malaria in terms of public health and social-economic impacts. A peculiar feature of these dioecious parasites is their ability to produce viable and fertile hybrid offspring. Originally only present in the tropics, schistosomiasis is now also endemic in southern Europe. Based on the analysis of two genetic markers the European schistosomes had previously been identified as hybrids between the livestock- and the human-infective species Schistosoma bovis and Schistosoma haematobium, respectively. Here, using PacBio long-read sequencing technology we performed genome assembly improvement and annotati…

MalePhysiologyIntrogressionEggsRC955-962SnailsDisease Vectors0302 clinical medicineMedical ConditionsReproductive PhysiologyArctic medicine. Tropical medicineInvertebrate GenomicsMedicine and Health SciencesBody SizeSchistosomiasis0303 health sciences[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]EukaryotaGenomics3. Good healthEuropeInfectious DiseasesSchistosoma bovisSchistosoma haematobiumSchistosomaFemalePublic aspects of medicineRA1-1270SchistosomesResearch ArticleEvolutionary ProcessesBulinus030231 tropical medicine03 medical and health sciencesHelminthsParasitic diseaseparasitic diseasesGeneticsParasitic DiseasesAnimalsHumans[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology030304 developmental biologyEvolutionary BiologyGenome Helminth[SDV.GEN]Life Sciences [q-bio]/GeneticsChimeraPublic Health Environmental and Occupational HealthOrganismsBiology and Life SciencesPaleontologyInvertebratesAnimal GenomicsEarth SciencesHybridization GeneticPaleogeneticsZoology
researchProduct

Morphological and genomic characterisation of the hybrid schistosome infecting humans in Europe reveals a complex admixture between Schistosoma haema…

2018

AbstractSchistosomes cause schistosomiasis, the world’s second most important parasitic disease after malaria. A peculiar feature of schistosomes is their ability to produce viable and fertile hybrids. Originally only present in the tropics, schistosomiasis is now also endemic in Europe. Based on two genetic markers the European species had been identified as a hybrid between the ruminant-infective Schistosoma bovis and the human-infective Schistosoma haematobium.Here we describe for the first time the genomic composition of the European schistosome hybrid (77% of S. haematobium and 23% of S. bovis origins), its morphometric parameters and its compatibility with the European vector snail an…

Schistosoma haematobium0303 health sciences030231 tropical medicineIntermediate hostSchistosomiasisBiologymedicine.diseasebiology.organism_classificationGenome3. Good health03 medical and health sciences0302 clinical medicineGenetic markerEvolutionary biologyParasitic diseaseVector (epidemiology)parasitic diseasesmedicine030304 developmental biologyHybrid
researchProduct