0000000001037346

AUTHOR

Ayşegül Varol

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Multi-omics approaches to improve malaria therapy.

2021

Malaria contributes to the most widespread infectious diseases worldwide. Even though current drugs are commercially available, the ever-increasing drug resistance problem by malaria parasites poses new challenges in malaria therapy. Hence, searching for efficient therapeutic strategies is of high priority in malaria control. In recent years, multi-omics technologies have been extensively applied to provide a more holistic view of functional principles and dynamics of biological mechanisms. We briefly review multi-omics technologies and focus on recent malaria progress conducted with the help of various omics methods. Then, we present up-to-date advances for multi-omics approaches in malari…

0301 basic medicineProteomicsPlasmodiumComputer scienceDrug ResistanceDisease03 medical and health sciencesAntimalarials0302 clinical medicineTreatment targetsBasic researchparasitic diseasesmedicineAnimalsHumansMetabolomicsPharmacologyGenomicsmedicine.diseaseMalaria030104 developmental biologyRisk analysis (engineering)Drug development030220 oncology & carcinogenesisMulti omicsMalaria controlMalariaPharmacological research
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