0000000001063227
AUTHOR
Rajitha Sadashiva
Synthesis, characterization, crystal structures and biological screening of 4-amino quinazoline sulfonamide derivatives
Three quinazolin-4-ylamino derivatives containing phenylbenzenesulfonamides (7a-7c) were synthesized by reacting (E)-N'-(2-cyanophenyl)-N,N-dimethyl formamidine (6) with different 4- amino-N-(phenyl)benzenesulfonamides (4a-4c) and characterized by different techniques such as HRMS, IR, 1H NMR and 13C NMR spectroscopy. The structural properties were further examined by single crystal X-ray diffraction method. The X-ray data shows that compounds 7a and 7c contain two molecules and 7b contains one molecule in the asymmetric unit. Comparison of conformation of two distinct molecules, “A” and “B”, in the asymmetric unit of 7a and 7c were studied with the aid of reported literature. The in vitro …
CCDC 1857204: Experimental Crystal Structure Determination
Related Article: A. Sunil Kumar, Jyothi Kudva, Manu Lahtinern, Anssi Peuronen, Rajitha Sadashiva, Damodara Naral|2019|J.Mol.Struct.|1190|29|doi:10.1016/j.molstruc.2019.04.050
CCDC 1857205: Experimental Crystal Structure Determination
Related Article: A. Sunil Kumar, Jyothi Kudva, Manu Lahtinern, Anssi Peuronen, Rajitha Sadashiva, Damodara Naral|2019|J.Mol.Struct.|1190|29|doi:10.1016/j.molstruc.2019.04.050