0000000001070623

AUTHOR

Claudia De Pasquale

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Th17 skewing in the GALT of a Crohn disease patient upon Lactobacillus rhamnosus GG consumption.

2015

We wish to report on a recent observation we made and that might represent a useful hint for the employment of the so called probiotics in the management of some pathological immune reactions of the gut. By analyzing GALT-associated T cells upon consumption of L. rhamnosus-GG, we obtained some hints that probiotics might have locoregional immunological effects mainly when administered in patients with IBDs rather than in individuals with non-inflamed gut mucosa.

0301 basic medicineSettore MED/17 - Malattie InfettiveImmunologyBioinformaticsPeyer's PatcheProbioticInflammatory bowel diseaseTh17 Cell03 medical and health sciencesPeyer's Patches0302 clinical medicineLactobacillus rhamnosusCrohn DiseaseIntestinal mucosaImmunology and AllergyMedicineHumansConsumption (economics)Settore MED/04 - Patologia Generalebiologybusiness.industryCrohn diseaseLacticaseibacillus rhamnosusInflammatory bowel disease; Intestinal mucosa; Lactobacillus rhamnosus; Mucosal barrier; Probiotics; T cell polarizationProbioticsbiology.organism_classificationMucosal barrierT cell polarization030104 developmental biology030220 oncology & carcinogenesisImmunologyTh17 CellsLactobacillus rhamnosubusinessHumanImmunology letters
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