0000000001072018

AUTHOR

Pietro Di Marco

showing 7 related works from this author

Escalating doses of paclitaxel and epirubicin in combination with cisplatin in advanced ovarian epithelial carcinoma: a phase I–II study

2003

Our objective was to identify a new active three-drug combination regimen consisting of paclitaxel (PTX), epirubicin (EPI) and cisplatin as first-line line chemotherapy for advanced ovarian carcinoma. A phase I study was carried out to evaluate the dose-limiting toxicity (DLT) and the maximally tolerated dose (MTD) of PXT and EPI in combination with a fixed dose of cisplatin every 4 weeks. Side-effects were recorded according to the NCI Common Toxicity Criteria. Patients were treated in cohorts of three with fixed-dose cisplatin 80 mg/m 2 and EPI 80 → 100 mg/ m 2 and PXT 100 → 160 mg/m 2 until DLT was reached. Once MTD was identified, a single-step phase II study was therefore carried out t…

AdultMaleCancer Researchmedicine.medical_specialtyAdolescentPaclitaxelmedicine.medical_treatmentUrologyPhases of clinical researchAntineoplastic AgentsPharmacologyAntineoplastic Combined Chemotherapy ProtocolsMucositisHumansMedicinePharmacology (medical)AgedEpirubicinNeoplasm StagingOvarian NeoplasmsPharmacologyCisplatinChemotherapyAntibiotics AntineoplasticDose-Response Relationship Drugbusiness.industryCarcinomaMiddle Agedmedicine.diseaseAntineoplastic Agents PhytogenicSurvival AnalysisRegimenOncologyToxicityAntiemeticsFemaleCisplatinbusinessFebrile neutropeniamedicine.drugEpirubicinAnti-Cancer Drugs
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Proteomic profiling of B-cell chronic lymphocytic leukemia. A pilot study.

2004

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Ricerca di Enterovirus in sedimenti marini delle coste siciliane

2007

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Proteomics Profiling of B-cell chronic lymphocitic leukemia

2004

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Systemic chemotherapy in elderly patients with locally advanced and/or inoperable squamous cell carcinoma of the head and neck: impact of anemia and …

2003

Abstract A review of the incidence and management of anemia in elderly patients with head and neck carcinoma treated with systemic chemotherapy. The role of recombinant human erythropoietin in preventing or correcting chemotherapy-related anemia has been focused. Data concerning the prospective use of recombinant human erythropoietin (rhEpo) in a series of unfit elderly patients (EPs) treated with carboplatin plus 5-fluorouracil. Patients were randomly assigned to receive subcutaneous rhEpo 10,000 U three times per week (TIW) (23 elderly patients) or no treatment (22 control patients). Recombinant hEpo was able to prevent anemia and to reduce transfusional requirements in treated patients a…

medicine.medical_specialtyAnemiamedicine.medical_treatmentAntineoplastic AgentsGastroenterologychemistry.chemical_compoundQuality of lifehemic and lymphatic diseasesInternal medicinemedicineHumansErythropoietinAgedChemotherapybusiness.industryIncidenceIncidence (epidemiology)AnemiaHematologymedicine.diseaseRecombinant ProteinsCarboplatinSurgeryOncologychemistryEpidermoid carcinomaHead and Neck NeoplasmsErythropoietinCarcinoma Squamous CellbusinessComplicationmedicine.drugCritical Reviews in Oncology/Hematology
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Proteomic profling of B-cell chronic lymphocytic leukemia

2004

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Proteomics of chronic lymphocyte leukemia B-cells

2004

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