0000000001077703

AUTHOR

Lo Iacono M

showing 3 related works from this author

CIGARETTE SMOKE EXPOSURE DOWNREGULATES TWO ISOELECTRIC VARIANTS OF HUMAN Hsp10 IN LUNG EPITHELIAL CELLS AND FIBROBLASTS: A PROTEOMIC STUDY.

2008

Settore BIO/16 - Anatomia UmanaHsp10 cigarette smoke oxidative stress proteomics
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Role of endothelial cell stress in the pathogenesis of chronic heart failure.

2009

Endothelial cells are key modulators of diverse physiological processes, and their impaired function is a cause of numerous cardiovascular diseases. Under physiologic condition, the reactive oxygen and nitrogen mediators in endothelia lead to the signal propagation of the initial stimulus, by forming molecules with a longer half-life like hydrogen peroxide. Hydrogen peroxide is the focus of growing attention in endothelial biology, and consequently the enzymes involved in its generation and clearance are viewed as novel mediators of great importance. In particular, among peroxidases, myeloperoxidase is recognized as a key enzyme, capable of impairing intracellular NO reservoirs as well as p…

Heart FailureEndotheliumbiologyEndothelial cells Myeloperoxidase Hydrogen Peroxide Oxidative Stress Enos Nitric Oxide Superoxide ROS RNS 3-Chlorotyrosine 3-Nitrotyrosine Nitrosylaton ReviewSuperoxideSettore BIO/16 - Anatomia UmanaOxidative phosphorylationmedicine.disease_causeNitric oxideCell biologyEndothelial stem cellchemistry.chemical_compoundOxidative Stressmedicine.anatomical_structurechemistryMyeloperoxidaseChronic Diseasemedicinebiology.proteinHumansEndothelium VascularReactive Oxygen SpeciesOxidative stressIntracellularPeroxidaseFrontiers in bioscience (Landmark edition)
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New perspectives on the roles of proteinases and lung structural cells in the pathogenesis of chronic obstructive pulmonary disease.

2007

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