0000000001082417

AUTHOR

Lény Teyssier

showing 4 related works from this author

Some Plant Defense Stimulators can induce IL-1β production in human immune cells in vitro

2020

8 pages; International audience; Among Plant Protection Products (PPP), a new emerging category of pesticides act by stimulating plant defense in order to improve plant resistance against microbial pathogens. Given that these compounds, the so-called Plant Defense Stimulators (PDS) act on innate immunity, we tested, using an in vitro approach on human mononuclear leucocytes (PBMC), the potential toxicity (XTT assay) and inflammatory effects (production of IL-1β) of 4 PPP belonging to different chemical families. We found that two products (LBG-01F34® and Regalis®) did not induce any cytotoxicity or IL-1 β production. The product BION-50 WG®, that contains Acibenzolar-S-methyl (ASM) and sili…

[SDV.IMM] Life Sciences [q-bio]/ImmunologyHealth Toxicology and Mutagenesismedicine.medical_treatmentXTT010501 environmental sciencesA vision for the future of pesticide toxicologyToxicology01 natural sciencesPeripheral blood mononuclear cellMicrobiology03 medical and health sciencesLaminarinchemistry.chemical_compound0302 clinical medicineImmune systemlcsh:RA1190-1270medicinePlant defense against herbivoryPesticidesCytotoxicitylcsh:Toxicology. Poisons0105 earth and related environmental sciencesInflammationCell metabolic activityInnate immune systemDanio rerioASM acyl-benzolar-S-methylZebra fishPBMCPlant Defense StimulatorIn vitro3. Good healthPPP Plant Protection productCytokinechemistryPDS Plant Defense StimulatorPBMC peripheral blood mononuclear cellsIL-1β[SDV.IMM]Life Sciences [q-bio]/Immunology030217 neurology & neurosurgeryToxicology Reports
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Lutter contre les infections bactériennes : le système immunitaire des plantes est aussi très efficace !

2016

SPE IPM UB CNRS Agrosup

0301 basic medicine[SDE] Environmental SciencesPlantes médicinalesrécepteurs PRRInfections bactériennes[SDV]Life Sciences [q-bio][ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionGeneral MedicineBiologyGeneral Biochemistry Genetics and Molecular Biology[SDV] Life Sciences [q-bio]03 medical and health sciences030104 developmental biologyplantes[SDE]Environmental Sciences[SDV.BV]Life Sciences [q-bio]/Vegetal Biology[SDV.BV] Life Sciences [q-bio]/Vegetal Biologyimmunité[SDV.AEN]Life Sciences [q-bio]/Food and NutritionComputingMilieux_MISCELLANEOUS
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Effect of commercially available Plant Defence Stimulators (PDS) on human innate immunity

2014

PDS (Plant defence stimulators) constitute a recent alternative to pesticides used for crop protection. These compounds called elicitors are of diverse nature, but they all act by stimulating innate immune system of plants. So, plants can better fight pathogens. Furthermore, there are many similarities in pathogen perception systems and cellular signalling in plants and animals. It is well established that many elicitors stimulate both human and plant innate immunity (Zipfel and Felix, 2005). Therefore, it is likely that human innate immunity could be modulated by PDS. The aim of this study is to evaluate pro/anti-inflammatory activity of five different commercially available PDS on human c…

PBMC (Peripheral Blood Mononuclear Cells)elictor;inflammation;toxicity;PBMC (Peripheral Blood Mononuclear Cells);human health;plant protection products;éliciteur;inflammation;toxicité;CMSP (Cellule mononucléaire du sang périphérique);santé humaine;produit phytosanitaireelictor[SDV]Life Sciences [q-bio]éliciteurtoxicityfood and beveragessanté humainehuman healthproduit phytosanitaireplant protection productsinflammationCMSP (Cellule mononucléaire du sang périphérique)[SDE]Environmental Sciencestoxicité[SDV.BV]Life Sciences [q-bio]/Vegetal Biology
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Étude des effets des stimulateurs des défenses naturelles des plantes sur l’immunité innée des vertébrés et mise en évidences des acteurs communs par…

2016

Les pesticides, utilisés pour protéger les cultures, ont souvent des effets délétères pour la santé humaine et l’environnement. Des alternatives telles que les SDN sont actuellement développées pour réduire leur utilisation. Compte tenu de la similarité des motifs moléculaires induisant l'immunité chez les plantes et les animaux, les SDN pourraient interagir avec le système immunitaire inné des vertébrés. Toutefois, lors du processus d'homologation des pesticides, aucun test ne s’intéresse directement à leurs effets pro/anti-inflammatoires bien que des maladies soient favorisées par l’inflammation chronique. En utilisant des cellules mononucléaires du sang périphérique humain, nous avons ét…

[SDV] Life Sciences [q-bio]these
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