0000000001082776

AUTHOR

Alessandra Splendiani

showing 3 related works from this author

AB0630 Cardiac Magnetic Resonance Imaging with Pharmacological Stress Perfusion in Asymptomatic Patients with Systemic Sclerosis

2016

Background Systemic Sclerosis (SSc)-heart disease (SSc-HD), although often clinically silent, significantly reduces the life-expectancy in these patients [1]. The cardiac magnetic resonance (CMR) is recognized useful tool for the diagnosis of SSc-HD and cardiac stress tests might be a helpful technique to highlight the occult myocardial involvement, which cannot be detected at rest due to compensatory mechanisms [2,3]. Objectives To evaluate the possible occult cardiac involvement in asymptomatic SSc patients by pharmacological stress, rest perfusion and delayed enhancement CMR, to identify as earlier as possible those patients at higher risk of cardiac related mortality and needing specifi…

medicine.medical_specialtymedicine.diagnostic_testbusiness.industryImmunologyArthritismedicine.diseaseAsymptomaticGeneral Biochemistry Genetics and Molecular BiologyRheumatologyCoronary arteriesmedicine.anatomical_structureRheumatologyCardiac magnetic resonance imagingVentricleInternal medicineImmunology and AllergyMedicineRadiologymedicine.symptombusinessPerfusionRheumatismAnnals of the Rheumatic Diseases
researchProduct

Pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance identifies very early cardiac involvement in systemic scler…

2017

Objective To evaluate occult cardiac involvement in asymptomatic systemic sclerosis (SSc) patients by pharmacological stress, rest perfusion and delayed enhancement cardiac magnetic resonance (CMR), for a very early identification of patients at higher risk of cardiac-related mortality. Methods Sixteen consecutive patients with definite SSc, fulfilling the American College of Rheumatology/European League Against Rheumatism 2013 classification criteria in less than 1 year from the onset of Raynaud's phenomenon, underwent pharmacological stress, rest perfusion and delayed enhancement CMR. At enrollment, no patient showed signs and/or symptoms suggestive for cardiac involvement. No patient sho…

AdultMalemedicine.medical_specialtyAdenosineHeart diseaseHeart DiseasesVasodilator AgentsContrast MediaMagnetic Resonance Imaging CineAsymptomaticCardiac magnetic resonance imaging with pharmacological stress; Myocardial perfusion defect; Systemic sclerosis; Systemic sclerosis heart involvement; Rheumatology030218 nuclear medicine & medical imaging03 medical and health sciencesMyocardial perfusion imagingCoronary circulation0302 clinical medicineRheumatologyPredictive Value of TestsInternal medicineCoronary CirculationCardiac magnetic resonance imaging with pharmacological stressMultidetector Computed TomographymedicineHumans030203 arthritis & rheumatologyScleroderma Systemicmedicine.diagnostic_testbusiness.industryMicrocirculationMyocardial Perfusion Imagingmedicine.diseaseRheumatologymyocardial perfusion defectSettore MED/16 - Reumatologiamedicine.anatomical_structureEarly DiagnosisVentriclecardiac magnetic resonance imaging with pharmacological streAsymptomatic Diseasessystemic sclerosis heart involvementSystemic sclerosisFemaleRadiologymedicine.symptombusinessPerfusionsystemic sclerosiRheumatism
researchProduct

640-Slice CT Measurement of Superior Orbital Fissure as Gateway for Light into the Brain: Statistical Evaluation of Area and Distance.

2016

Objective Our aim was to provide normative data concerning superior orbital fissure area (SOFA), ocular skin and the substantia nigra (D-SS) and orbital fissure and the substantia nigra (D-SOF-S) distances by CT scan in adult Caucasian population. Methods The area of the superior orbital fissure (SOF), the distance between the ocular skin and the substantia nigra and the distance between the superior orbital fissure and the substantia nigra using CT and 3D-CT images. Results Normative data stratified for age and gender were obtained. The data here reported show that some degree of variability in SOFA, D-SS and D-SOF-S measurements can be observed healthy Caucasian subjects. Gender stratifie…

Normal Distributionlcsh:MedicineComputed tomographyDistance MeasurementNervous System030218 nuclear medicine & medical imagingDiagnostic RadiologyMidbrain0302 clinical medicineMedicine and Health SciencesMedicineCaucasian populationlcsh:ScienceTomographyMeasurementMultidisciplinaryMovement Disordersmedicine.diagnostic_testNervesOrbital fissureRadiology and ImagingCranial NervesBrainNeurodegenerative DiseasesParkinson DiseaseSubstantia Nigramedicine.anatomical_structureNeurologySuperior orbital fissurePhysical SciencesEngineering and TechnologyAnatomyBrainstemBright lightResearch ArticleImaging TechniquesOcular AnatomySubstantia nigraNeuroimagingResearch and Analysis MethodsMidbrain03 medical and health sciencesDiagnostic MedicineOcular SystemPathologicalbusiness.industrylcsh:RBiology and Life SciencesProbability TheoryProbability DistributionComputed Axial Tomographylcsh:QbusinessNuclear medicine030217 neurology & neurosurgeryMathematicsNeurosciencePloS one
researchProduct